| Objective: To explore the curative effect of Lixin I on CHF with VPCs through examining the QTd QTcd of 12-leads body electrocardiogram and 6 minutes walk test in patients.Methods: Forty cases were randomly devided into treatment group and control group. Patients in the control group were treated by west medicine, while patients in the treatment group were treated by Lixin I 150ml every time and twice every day on the basis of conventional treatment. Detecting the changes of QTd QTcd in the two groups of patients. At the same time, according to the method in the Vera Bittner's report, the change were observed by 6 minutes walk test before and after the treatments. The curative effect on CHF in Lixin I was also observed.Results: The QTd QTcd of the treatment group had degraded more obviously than that of the control group, and the difference was significant(P<0.01). The index of patients' heart function such as the distance of 6 minutes walk test EF FS and E/A had improved greatly(P<0.05).The treatment group outweighed the control group in the aspect of clinical evolution(P<0.05).Conclusions:1. Lixin I could improve the 6MWT ES FS E/A greatly of the patients on CHF with VPCs. These evidents show Lixin I could improve the heart's founction.2. Lixin I could decrease the QTd QTcd of the patients on CHF with VPCs obviously, which revealed the mechanism of action against cardiac failure could be the regulation of endocrine system in the patients with CHF by using Lixin I.3. Lixin I is an effective prescription, depending on the basic law which is tonifying pneuma, warming Yang, promoting blood flow and using diuretic of gydragogue to alleviate water retention.
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