The Protective Effect Of Physalis Peruviana L On Induced Senstitive Liver Injury In Rats

Objective: To observation sends the sensitive ratwhether truly has the liver damage, to investigate theinfluence of physalis Peruviana L on OVA induced senstitiveliver injury. To approach the medicinal purposes part ofchildren food allergy.Methods: Preparation small rat allergy model. Fill thedifferent density the physalis Peruviana L's fruit and calyxshuitiwu. Adopting blood and liver and indirect determinationblood serum IgE and ALT level; liver pathological changesunder microscope were observed. Histochemistry dyeingexamines the TNF-α,IFN-γmasculine gender rate. And Calyxgroup's fuction conducts the comparison rearch to the fruit.Results: 1.The stimulations groups rat IgE,ALT,TNF-α,IFN-γObviously elevates content; 2.The high and middledoseage of might inhibit the dermato-allergic reaction of ratand mitigating the inflammation of intestine. Blood serumIgE and ALT in the model group were higher than in normalcontrol group (p＜0.01) the quantity of TNF-α,IFN-γwere higher than in normal group(p＜0.01). Which proved that OVAintravenously had already led to rat liver damage. Calyxgroup'change is more oboiously.Conclusions: 1) Outside sends the sensitive rat exceptthe intestinal tract, the skin, the respiratory tract inflammationchanges, truly has the obvious liver damage, this kind ofdamage is the fast hairstyle immune response which maybelies between by IgE leads, and the cell factor TNF-α,IFN-γhas the close relation. 2) The high and middledoseagesphysalis Peruviana L's fruit and Sue sends the sensitive rat'simmunity liver damage to the OVA to the obviously protectivefunction. 3) To compare with fruit and Calyx to the OVA withthe result that the anti-inflammation. Anti-allergy fuction ismore obviously. 4) The physalis Peruviana L has somepossibly curative effect of children food allergy.