A Clinical Study On The Relationship Between Microcirculation Disturbance And Sudden Deafness

Objective: To investigate the etiology of sudden deafness and analyze the relationship between microcirculation disturbance and sudden deafness. Methods: The medical histories of 135 patients with sudden deafness were collected. Clinical laboratory parameters including clinical chemistry, hemorheology,hematology and hemostasis determinations in these patients were measured and compared with 30 healthy age-matched control subjects. The contrast enhanced MR imaging, CT(Compute Tomography )and TCD (Transcranial Doppler). were also performed in the 135 patients with sudden hearing loss. Result: The index of hemorheology, WBC, NEUT and serum lipid changes in patients with sudden deafness were significantly different from those in the control subjects (P<0. 05). The white collar workers with psychological and behavioral abnormality tend to suffer from sudden deafness. Of the 135 patients with sudden deafenss, 3 cases of acoustic neuroma were found by MRI, 19 cases of vertebrobasilar artery insufficiency by DCEMRA, 1 case of large vestibular aqueduct syndrome by CT, and 23 patients with abnormal cerebral blood-flow velocity by TCD. Conclusion: The current study indicates that the microcirculation disturbance is apparently closely related to the occurrence of sudden deafness.