The Research Among With Antibody To Cyclic Citrullinated Peptide,Rheumatoid Factor And The Types Of Syndrome Of Traditional Chinese Medicine On Rheumatoid Arthritis

Objective: To study the correlation among with antibody to cyclic citrullinated peptide(anti-CCP), rheumatoid factor(RF), radiographic progression, the physical quantization signs of arthritis and the types of syndrome of Traditional Chinese Medicine on the rheumatoid arthritis Methods: To choose 166 patients who fit the diagnostic criterias of West and Traditional Chinese Medicine as study objects, coming from the department of Traditional Chinese Medicine, rheumatism of the first affiliated hospital of Xinjiang medical university and the department of rheumatism in the hospital of Traditional Chinese Medicine of Xinjiang uygur autonomous region.With comprehensiveanalysis by the four examination methods to carry out dialectical grouping and to detect anti-CCP, RF, radiographic progression and the physical quantization signs of arthritis on the time of visting or the first three days to be in hospital. Results: There were discrimina-tion among with the five types on the positive and negative probability of anti-CCP, x~2 =10.262 (P=0.036); as compared to the type of humid heat impotency, the type of stagnated blood impatency had the higher positive probability of anti-CCP, x~2=8.25 (P=0.004); there were no discrimination among with the five types on the positive and negative probability of RF, x2 =2.034 (P=0.7295); there were no discrimination on the positive and negative probability between the above-mentioned methods-anti-CCP and RF, x~2 =2.421 (P=0.120), however, there was a positive correlation between anti-CCP and RF, R=0.567 (P=0.000001); the types of stagnated blood impatency, hepatic and renal yin deficiency, deficiency cold of kidney-QI had higher grade of radiographic progression than the types of cold hygrosis and humid heat impotency, P<0.01; the tendency of age in the type of higher-grade radiographic progression was older than the lower-grade, P＜0.01, the tendency of the courses of disease in the higher-grade radiographic progression was longer than the lower-grade, P＜0.01; in the type of humid heat impotency, there were higher lever of ache, limitation of activity and arthrocele than the type of deficiency cold of kidney-QI, P<0.01 Conclusions: there were discrimination among with the five groups on the positive and negative probability of anti-CCP and no discrimination on the positive and negative probability of RF, however, there was a positive correlation between the two methods; there were develping tendency on the radiographic progression and dialectical grouping with the increasing of the years of age and the courses of disease; there were higher lever of arthritis representation in the type of humid heat impotency than the type of deficiency cold of kidney-QI.