Multivariate Regression Analysis Of Postoperative Complications Of Resection Of Big Hepatocellular Carcinoma.

Objective:To study the factors associated with postoperative complications of resection of big hepatocellular carcinoma Methods:Consecutive 58 cases of hepatocellular carcinoma which were 5-10cm rescted between Jan 2005 and Jun 2007 at Xinjiang Tumor Hospital were summarized retrospectively. Single variant and multivariate stepwise regression model were used to analysis the factors associated with postoperative complications age,tumor site,blood transfusion of resection of big hepatocellular carcinoma. Results:The overall morbidity rate andmortality rate were 20.7%. Single variant analysis showed that the age, liver function child-pugh, intraoperative blood loss and blood transfusion were associated with postoperative complications. Furthermore, multivariate stepwise regression analysis revealed that the age, intraoperative blood loss and blood transfusion volume were the independent risk factors of morbidity rate of resections of hepatocellular carcinoma Conclusions:The long survival of big Hepatocellular carcinoma is depended on the tumor,treatment factor,age, liver function child-pugh and blood transfusion,which are the important factor infecting the postoperative complications.Increasing liver function reserve before operation choose a proper restting range intraoperation controlling the intraoperative hemorrhage and blood transfusion are the important to prevent the postoperative complication.