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An Investigation On The Status Of Hepatitis B Among Normal Population In Chaohu City

Posted on:2009-08-05Degree:MasterType:Thesis
Country:ChinaCandidate:F Y GeFull Text:PDF
GTID:2144360242987073Subject:Epidemiology and Health Statistics
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An investigation on the status of Hepatitis B among normal population in Chaohu cityObjective To analyze the epidemic characteristics of Hepatitis B,and provide the basis for taking preventive measures .Methods A cluster sampling method was conducted to perform questionnaire on 1957 healthy persons which were selected randomly from urban and rural population of Chaohu. The general features, post history, family history, disease contact history were investigated. 3ml venous blood was gathered. Use ELISA to check HBsAg and HBsAb; persons with the HBsAg positive take further examination about five items of hepatitis B. The results were analyzed by SPSS 13.0 softwares.Results 1957 persons were tested, among which 183 were HBsAg positive,accounting for 9.35%.878 were HBsAg positive,accounting for 44.86%.There were no statistic significances of the HBsAg and HBsAb positive rates between different gender group and urban / rural group. There were no statistic significances of the HBsAg positive rates between age groups and occupational groups in urban population, but HBsAg positive rates in the different levels of education have statistic significances. There were statistic significances of the HBsAg positive rates between age groups and occupational groups in rural population, however, no statistically significant different were shown between educational groups. Single factor analysis showed that family members with hepatitis B (OR=3.42,P<0.01),unsafe injection (OR=1.42 , P <0.01),using razor together (OR=1.92 , P<0.01),tooth extraction (OR=2.14,P <0.01),ear piercing (OR=1.36,P <0.05),hospitalization (OR=1.75,P <0.05),tattooing (OR=3.32,P <0.05),without Hepatitis B vaccination (OR=1.52,P<0.05) were the risk factors of HBV infection. Through the Multivariate analysis of risk factors on Hepatitis B infection, family members with hepatitis B(OR=3.49,P <0.01), using razor together(OR=1.73,P<0.05), tattooing(OR=3.71,P<0.05), without Hepatitis B vaccination (OR=1.86,P<0.01) were the primary risk factors of HBV infection.Conclusion The rates of HBsAg-positive and HBsAb-positive in Chaohu were higher. Through the Multivariate analysis of risk factors on Hepatitis B infection, Family members with hepatitis B, using razor together, tattooing, history of immunization were the primary risk factors of HBV infection. In order to reduce the rate of Hepatitis B infection, we should take effective measures to avoid its risk factors. The distribution characteristic of which is different between cities and countrysides. As a result, it is necessary to enhance the propaganda of immunifaction among normal population in Chaohu city. An investigation on the status of cognition about hepatitis B and inoculation rate of hepatitis B Vaccines among normal population in Chaohu cityObjective In order to find out the status of cognition about hepatitis B and inoculation of hepatitis B Vaccines among normal population in Chaohu city. and provide the basis for taking preventive measures.Methods A cluster sampling method was conducted to perform questionnaire on 1565 healthy persons which were selected randomly from urban and rural population of Chaohu. The general features, post history, family history, disease contact history were investigated. 3ml venous blood was gathered. Use ELISA to check HBsAg and HBsAb; persons with the HBsAg positive take further examination about five items of hepatitis B. The results were analyzed by SPSS13.0 softwares.Results 1565 persons were tested, the inoculation rate of hepatitis B Vaccines was 12.08%, and the whole course vaccine inoculation rate was 8.88%. There were statistic significances of the inoculation rate of hepatitis B Vaccines among age groups,educational level, gender group ,domestic economy status and urban / rural group. There were no statistic significances of the whole course vaccine inoculation rate between different gender groups. However, the whole course vaccine inoculation rate in the different levels of age groups,educational level, domestic economy status and urban / rural group have statistic significances. urban population, educational level were the primary favorable factors of the inoculation rate of hepatitis B Vaccines, Single factor analysis showed that elder age(OR=0.42,P<0.01) was the risk factors of the inoculation rate of hepatitis B Vaccines and males(OR=0.42,P<0.05),higher educational lever(sOR=2.92,P<0.01), urban (OR=1.95,P<0.01), domestic economy status (OR=1.95,P<0.01)were the protective factors of the inoculation rate of hepatitis B Vaccines. Multivariate analysis showed that urban (OR=1.53,P <0.05), higher educational levers(OR=1.77,P<0.01) were the primary protective factors of the inoculation rate of hepatitis B Vaccines and elder age(OR=0.49,P<0.01) was the primary risk factors of the inoculation rate of hepatitis B Vaccines.Conclusion The distribution characteristic of the inoculation of hepatitis B Vaccines is different between cities and countryside. It is necessary to enhance the propaganda of immunifaction. Maybe we could raise the inoculation rate of hepatitis B Vaccines, improve people's attitude to type B hepatitis through enhancing propaganda of the cognition about hepatitis B.
Keywords/Search Tags:Hepatitis B virus, Seroepidemiologic studies, normal population, Viral hepatitis vaccines
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