Expressing And Clinical Meaning Of Survivin, P53 Protein In Squamous Cell Esophagus Cancer Of Xinjiang Uygur Nation

Objective:To discuss the correlation effect of expressing and clinical pathology of survivin,p53 in squamous cell esophagus cancer of xinjiang uygur nation,and discuss affect of happening,development of esophagus cancer.Methods:using the immunohistochemical method(Envision two stage assay method),to examine the expressing of survivin and p53 protien in 18 normal esophageal professional jargon borderline tissue and in 50 squamous cell esophagus cancer tissue,analysis the correlation of clinical pathology index,results:in 50 squamous cell esophagus cancer tissue masculine rate of survivin were 66%,p53 were 38%,obviously hirgher than(normal esophageal professional jargon borderline tissue)(p＜0.5);masculine rate of survivin and p53 protien in middlelate esophagus cancer higher than morning stage esophagus cancer(p＜0.5);the expressing of survivin and p53 protien in differential stimulus squamous cell esophagus cancer have significant difference(p＜0.5)and no relation between the patient's sexuality,age and aversion of lymphatic gland(p＜0.5);there is no dependablity the expressing of survivin and p53 protien in squamous cell esophagus cancer(r=0.040,p＜0.5). conclusion:squamous cell esophagus cancer tissue masculine rate of survivin and p53 protien obviously hirgher than normal esophageal tissue(p＜0.5).the expressing of protien have significant difference in clinical stage and pathologic differential stimulus,to judgment the malignancy of squamous cell esophagus cancer and conclude clinical prognosis.