Study On Varicocele Cases Associated With Oligozoospermia Or With Asthenospermia By Buzhong Yiqi Decoction And L-carnitine

[Objective]To observe the therapeutic effect of Buzhong Yiqi Decoction combining L-carnitine for varicocele cases associated with oligozoospermia or with asthenospermia.To discuss the pathological mechanism of it and to explore the possible mechanism of improving the sperm density and motility.[Methods]50 cases of varicocele infertility according to the accepted standard were enrolled and divided into two groups randomly:the treatment group(25cases)received Buzhong Yiqi Decoction combining L-carnitine therapy; while the control group with 25 cases received only L-carnitine.After three monthes of therapy,to evaluate the clinical effection and compare the sperm density,sperm vitality and sperm motility.The semen characteristics were carried out by the computer-aided semen analysis(CASA)technique.All the data were analysised by SPASS13.0.[Results]The general effective rate of treatment group was 90.91%,through Ridit analysis,the treatment group was obviously superior to the control group.Compared with the control group in terms of vitality of sperm,through F test,the treatment group was superior(P<0.05).There were significant differences between the treatment group and the control group referring the sperm density and(A,A+B)grade sperm percentage(P<0.01),the treatment group was obviously superior.On the other hand,through X~2 test,the clinical symptom were markedly improved in contrast to before(P<0.01).In terms of density, vitality and movable ratio,through T test,there were differences between post-treatment and pre-therapy of the treatment group and the control group (P<0.01),both of the team were effective on improving the sperm density and motility.[Conclusion]Therapy of Buzhong Yiqi Decoction combining L-carnitine varicocele infertility could not only release varicocele symptom,but also better the quality of semen,and improve the density,vitality and movable ratio of sperm.The pathological mechanism could be disturbance of Qi,Xue and Jing,deducing from the research.L-carnitine was eutherapeutic and safe medicine for male infertility,but the mechanism of action needed further research.