The Effects Of Different Options In Ectopic Pregnancy Conservative Treatment

Ectopic pregnancy is the zygote in the uterus outside the body cavity of implantation,it is one of obstetrics and gynecology common acute abdomen. In recent years due to the increase in the incidence of pelvic inflammatory disease,treatment technology applications, and other factors, the incidence of ectopic pregnancy upward trend, it is about 1%, it is one of the major causes of death in gynecology and obstetrics patients. Tubal pregnancy in which is the most common. Ectopic pregnancy treatment methods are conservative treatment and surgical treatment, the traditional treatment is surgical treatment, transvaginal ultrasound and blood human chorionic gonadotropin (β-HCG) testing two methods of combining the application of ectopic pregnancy Early diagnosis of a higher degree of sensitivity and specificity, the majority of ectopic pregnancy can be diagnosis before the broken, and early diagnosis of ectopic pregnancy to be conservative for the treatment of the timing and conditions.The conservative treatment of ectopic pregnancy, including drug treatment and looking forward to treatment, drug treatment, including systemic and local drug administration. Among them, methotrexate (methotrexate, MTX), mifepristone (mifepristone, RU486) as an effective conservative treatment is commonly used drugs. Ultrasound treatment is between surgical intervention and non-operation between a minimally invasive treatment. 1987, Feichtinger first reported in the ultrasound-guided injection MTX 10 milligrams (mg) of the success of the treatment of ectopic pregnancy. After that, MTX in the clinical treatment of ectopic pregnancy applications have increased, it becomes the most widely used drug treatment of ectopic pregnancy, this study of ectopic pregnancy conservative treatment options for the effect to compare.Objective: Ectopic pregnancy explore different methods of conservative treatment of clinical efficacy.Methods:Retrospective analysis of the Second Hospital of Dalian Medical University Obstetrics and Gynecology in January 2004 to February 2008 between the diagnosis of ectopic pregnancy to different methods of conservative treatment in patients with 96 cases, according to standards into revenue, according to different treatment is divided into A ,B,C,D four groups. Four patients in the average age of menopause average number of days, before treatment bloodβ-HCG value, ectopic pregnancy mass diameter comparison, the differences were not statistically significant (P> 0.05). A group for patients with systemic application of MTX treatment, C patients in the ultrasound-guided injection of ectopic pregnancy sac puncture MTX, B, D, respectively in the two groups A, C and on the basis of two groups of patients with oral mifepristone. Bank of ways, the four groups of patients with a success rate, bloodβ-HCG changes in the value, mass narrow margin, hospitalization, medication after adverse drug reactions compared to observe and record results using statistical analysis, To evaluate ectopic pregnancy conservative treatment of the effects of different options, the effect for which to compare.Results:1.Four groups of patients with treatment of comparison: Bank of ways, the success rate of 4 groups of patients, mass narrow> 30% rate, the average hospital stay by a recorded and compared to the successful treatment of several patients and the success rate for A group of 15 cases (65.2%), B group of 17 cases (77.3%), C Group of 21 cases (84.0%), D Group 25 cases (96.2%). Losers were diverted to emergency surgery. Four groups of patients with treatment success rate of statistical difference was significant (P <0.05). D component of the maximum power, mass narrow> 30% of the highest rates, the shortest average hospital stay. 2. Before and after treatment bloodβ-HCG the changes: four groups were calculated with the seventh day of bloodβ-HCG value relative to the treatment of blood beforeβ-HCG value of the rate of decline, A group bloodβ-HCG decline rate was 30.12+5.69%, B group bloodβ-HCG decline rate was 45.52+8.98%, C group bloodβ-HCG decline rate was 52.87+3.57%, D group bloodβ-HCG rate dropped 5.69 percent to 61.08. Four groups of patients withβ-HCG rate of decline compared statistical difference was significant (P <0.01), of which the blood of Group Dβ-HCG the largest rate of decline. 3. Adverse drug reactions: a record four groups of patients treated in the various adverse effects, including gastrointestinal reaction, oral ulcers, bone marrow suppression, liver damage, calculated four groups of patients with toxicity of rates, results The statistical difference was significant (P <0.05), which in Group D of the least adverse reactions.Validity. The effect for which to compare.Conclusion:In the early un-ruptured tubal pregnancy, ultrasound-guided puncture capsule of ectopic pregnancy and oral mifepristone and methotrexate therapy is an ideal method of treatment,changed the traditional surgical treatment.It achieves a minimum of surgical intervention so that patients do not suffer from the surgical treatment,and to preserve the patient's fallopian tube more suitable for the requirements of maternity patients, and the operation is simple, safe and effective, is an effective method of treatment.