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The Study Of The Relationship Between The Lipid Indexes And Deep Vein Thrombosis Of Lower Extremity

Posted on:2009-04-16Degree:MasterType:Thesis
Country:ChinaCandidate:Y YangFull Text:PDF
GTID:2144360245984253Subject:Internal Medicine
Abstract/Summary:PDF Full Text Request
[Objective]To explore the relationship between the lipid indexes and deep vein thrombosis (DVT) of lower extremity by the study of the lipid indexes between 108 patients of DVT of lower extremity and 100 patients as compared group.1. To understand the relationship between every indexes of the lipid such as: CHOL, TRIG, LDL, HDL, LDL and ox-Lp (a), and DVT of lower extremity.2. How to evaluate the danger of DVT of lower extremity and to carry out it better according to the level of the lipid indexes.[Methods]1. First 120 patients of traction was random selected in hospital, as experimental group; and 100 patients of non-traction was random selected in the same time and condition, as control group. Than the incidence of DVT of lower extremity of the two groups was analyzed statically, draw the conclusion, and then understand if traction can affect the incidence of DVT of lower extremity.2.108 patients who were in bed after injury formed DVT of lower extremity within two weeks, were divided into two groups (experimental group): traction group (B1) and non-traction group (B2), and there were 100 patients who didn't form DVT of lower extremity were divided into two groups (control group): traction group (A1) and non-traction group (A2). The lipid level of these patients who were in bed after injury one day, one week and two weeks were analyzed retrospectively, including: CHOL, TRIG, LDL, HDL, ox-LDL and Lp(a). First, we can understand the affection of traction by compare between the group Al and A2 and group B1 and B2, than we can understand the relationship by compare differences of lipids in the various indicators of between the various groups.[Results]1. Among the 120 patients of group traction there were 20 patients suffer from DVT of lower extremity, incidence of DVT of lower extremity was 16.7%; Among the 100 patients of group non-traction there were 15 patients suffer from DVT of lower extremity, incidence of DVT of lower extremity was 15%. By chi square test, X~2=0.113(P>0.05), so we can't consider incidence of DVT of lower extremity of the two groups is different.2. Compared between group A1 and B1 and between group A2 and B2 showed that: CHOL and TRIG, there were no different between the experimental group and the control group; but level of ox-LDL of the experimental group was significantly higher than the control group, the experimental group; level of LDL and HDL of the experimental group after two weeks was significantly higher and lower than the level of the control group; level of Lp (a) of the experimental group after one week and two weeks was significantly higher than the control group.[Conclusions]1. It is not regarded induced factor of DVT of lower extremity that bone was tracked, and it doesn't affect DVT of lower extremity.2. CHOL and TRIG have no relevance with DVT of lower extremity.3. The increase of Ox-LDL, LDL, HDL and Lp (a) levels have relevance with DVT of lower extremity, in particular ox-LDL have significantly relevance with DVT of lower extremity, it is an important factor in the formation of venous thrombosis and has great significance .4. To higher Ox-LDL level patients elevated should actively prevent the formation of DVT of lower extremity, so as to avoid serious consequences, such as pulmonary embolism, a life-threatening. And LDL, HDL and Lp (a) levels can be used as auxiliary indicator to the prevention of DVT of lower extremity.
Keywords/Search Tags:DVT of lower extremity, lipids, ox-LDL, Lp (a), vascular Doppler
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