Preparation And Evaluation Of Rukang Cataplasmata

Systematical research of the compound prescription of TCM has been performed in this study Cataplasmata is used to treat the cyclomastopathy. The contents of the study include: 1.the study of extraction technology;2.the study of formation technique;3.the study of in vitro transdermal absorption;4.the study of quality standard;5.the study of initial stability;6. the study of pharmacodynamics. The extraction technology of mustard oil of White Mustard Seed,The alcohol extraction technology of Corydalis Tuber, Evodiae Fruit, Paeoniae Radix and Cowherb Semen(stir-baking to crack),The high proportion alcohol extraction technology of Olibanoresin and Gum Myrrh is optimized by orthogonal test.The optimum proportion of matrix for the preparation process of Rukang Cataplasmata is selected by orthogonal test. Modeling technique of Rukang Cataplasmata is further ascertained. A check-up for adhesive power,nonflowing,content of cream is founded. The result shows Rukang Cataplasmata which is made by preparation condition of this test accords with concerned regulations of Cataplasmata. Using Franz diffusion pool,the total penetration amount of evodiamine and rutacarpine in Rukang Cataplasmata at different times was compared rapidly by HPLC.Corydalis Tuber, Evodiae Fruit, Paeoniae Radix, Olibanoresin,Gum Myrrh, Borneolum Syntheticum and Muscone are qualitatively tested by TLC. The total amount of evodiamine and rutacarpine is quantitatively analyzed by HPLC. The experiments show that Rukang Cataplasmata has good stability in three months.The study of pharmacodynamics show that Rukang Cataplasmata have a value for clinic and a feasibility for further development.