Effect Of Multi-rehabilitation On Quality Of Life In Children With Cerebral Plasy

Objective:To investigate impact of cerebral palsy(CP) on children's quality of life(QOL).Clinical observation of multi-rehabilitation on QOL and condition in children with CP.Methods:A ease-control and before-after study of the experimental design method.Selected inpatients with CP as the CP group,randomly selected healthy peers from two kindergartens in Nanhai area as the normal-control group,and selected inpatients with acute upper respiratory infection as common-disease-control group.All children were measured by Pediatric Quality of Life Inventory Version 4(PedsQL4.0) to assess their QOL and then compared differences in QOL of children among three groups.Children with CP were also assessed gross motor function by Gross Motor Function Measure(GMFM) and developmental quotient(DQ) by Beijing Gesell Developmental Scale(GDS) before and after treatment.Relationship was analyzed among QOL,clinical classification,anatomical type,condition and intelligence of children with CP.Children with CP were treated by multi-rehabilitation combined of modern medicine,traditional medicine and family medicine in three months and then compared differences in QOL,gross motor function and DQ before and after treatment.Results:200 children participated in all(80 cases in CP group,80 in normal-control group and 40 in common-disease-control group).There was no significant differences in children' s age and gender,as well as parents' age, sex,educational background and income among three groups.Significant differences in mean scores favoring two control group were found in physical functioning/aspect,emotional functioning,social functioning,psychological aspect and total score(P＜0.01).There was no significant differences in mean scores of PedsQL4.0 in all clinical types of children with CP.Significant differences in mean scores between spastic quadriplegia and spastic diplegia of children with CP were found in physical functioning/aspect and total score(P＜0.01),except emotional functioning,social functioning and psychological aspect.Mean scores of different level of GMFCS(Gross Motor Function Classification System),as well as different level of intelligence in children with CP were found significant differences in physical functioning/aspect,social functioning,psychological aspect and total score(P＜0.05),but with no significant differences in emotional functioning. GMFM total scores and social adaptation DQ of children with CP positive correlated to their physical functioning/aspect,social functioning, psychological aspect and total score(P＜0.01),but with no significant correlation to emotional functioning.After three months treatment of multi-rehabilitation,32 cases of CP were selected by convenience sampling method.12 cases showed significant effect(37.5%),11 cases showed progress(34.4%),and 9 cases had no-effect(28.1%)(total probability of effective is 71.9%).Children's GMFM seat score,station scores and total scores were significant different before and after treatment(P＜0.05).After 3 months rehabilitation there was some improvement in PedsQL4.0-QOL,but with no significant differences.Conclusion:CP reduces children's QOL in full-scale.QOL positive correlates to gross motor function,as well as level of intelligence of children with CP.Multi-rehabilitation can improve children' s condition and gross motor function.After 3 months rehabilitation,there is no significant improvement in children's QOL.