| Background:Similar to heart, gastrointestinal tract movement depends on the electrical-mechanical coupling mechanism, the contraction of gastrointestinal smooth muscle is based on their self-generated slow-wave potential (SW). Slow-wave potential due to a constant rhythm and started in the junctiong of the stomach fundus and stomach corpus (great curvature side). So it is possible that the "gastric pacemaker" exist here, whose fuction is like the the heart sino-atrial node. Under normal circumstances the stomach through the gastric smooth muscle from slow-wave under the Cajal interstitial cells (ICC) network from the proximal of the corpus to the pylorus. When abnormal gastric slow-wave potential of the basic electrical rhythm ( BER) will be caused by changes in gastric dysrhythmia, and the impact of gastric smooth muscle contraction, so that delayed gastric emptying the contents of retention. Excision of part of the stomach is caused by abnormal slow-wave potential of one of the factors of postoperative delayed gastric emptying (DGE) and more slow-wave rhythm with stomach disorders.Objective:1,Confirming the existence of the "gastric pacemaker" by surgical method.2,Observing the relation ship between the different parts of the surgical site of measured site to the Gastric Dysrhythmia then deducing some law of the slow wave conduction from the result.Method:Experimental research on animals, 18 rabbits, in accordance with the principle of completely randomized into three treatment groups, each group 6. Observe the natural recovery process after 3, 10, 20 points, pacing the stomach resection group, the greater curvature side of gastric body distal wedge resection group (non-gastric pacemaker removal group), the control group (abdominal switch) near Gastric pacing and normal antral slow wave frequency and percentage of normal slow-wave (normal range percent, N%). Proof of statistical methods used in different parts of the stomach in the stomach after gastric wedge resection of gastric electrical rhythm and the difference between the basic electrical rhythm.Results:Factorial design based on analysis of variance and 1-1 compared to the results of the analysis of variance: resection of different parts of the stomach after gastric electrical rhythm of the impact of different(P<0.05); different parts of the stomach after gastric electric rhythm different(P<0.05); surgical resection of different parts of the stomach after rhythm and speed of recovery are different(P<0.05); in different parts of the stomach after electrical rhythm and speed of recovery are different(P<0.05); surgical resection of different parts would lead to different parts of the stomach after gastric electrical rhythm of the difference(P<0.05).Conclusion:1, "Pacemaker area" exists at the junction of the proximal gastric corpus and fundus. (great curvature side).2. Resection of the proximal gastric body compared with the resection of gastric body, the former caused by postoperative gastric dysrhythmia is more serious and the degree of restoration of slower; antral Office Department as compared with the gastric body, which occurred in the postoperative gastric dysrhythmia the extent of the restoration of a more serious and slower. 2. Gastric wedge resection can cause postoperative dysrhythmia of the stomach, however, resulted in removal of different parts of the degree of EGG disorder is different from that cells in different parts of the stomach, "self-discipline", this may be related to cells in the stomach ICC in different parts of the distribution of due to differences in the number and subtypes.Innovation:In this experiment through the removal of different parts of the stomach so that changes in gastric electrical rhythm, upon inquiry, on the partial resection of the stomach and gastric electrical rhythm of the relationship between changes, there is no reported literature. |
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