The Analysis Of Ultrasound Characteristics And The Comparison Of PEIT Therapeutic Efficacy Of Different Histio-pathology Types Of Primary Liver Cancer

Objective To evaluate the ultrasounic characteristics and compare the therapeutic efficacy of percutaneous ethanol injection treatment(PEIT) of different histio-pathology types of primary liver cancer, wish to elevate the ability of applications of ordinary ultrasound examination in diagnosis and treatment of primary liver cancer. Methods (1) Retrospective analyze the preoperative ultrasound examination results including the echo intensity,tumor locality,definition of tumor edge,tumor numbers and distribution of gender of 552 cases of pimary liver cancer in Eastern Hepatobiliary Surgery Hospital from April to October in 2007 who have been operatived later,divide them to three groups as hepatocellular carcinoma(HCC),Intrahepatic cholangiocarcinoma (ICC) and mixed hepatic carcinoma according to the histio-pathology types after operating and get the correlation ship of every group through SPSS statistic software.(2) choose and follow-up to visit 34 HCC patients and 25 ICC patients who were all postop and had recurrence tumor(diameter≤3cm and numbers≤3 ) those had been treated by PEIT. Compare and analyze the therapeutic efficacy. Results Statistic the ultrasound characteristics according to the histo-pathology results using chi-square test and get the results as follows:P(echo intensity)=0.085,P (tumor locality)=0.024,P(definition of tumor edge)=0.001,P(distribution of gender)=0.005,P ( tumor numbers ) =0.402。The tumor locality,definition of tumor edge,distribution of gender of different histo-pathology types have statistical signification. The echo intensity and tumor numbers haven't statistic signification. But if divid the groups as the echo intensity and statistic the tumor diameters using ANOVA, we can get P=0.000, so the diameter of different echo intensity groups has statistical signification. (2) Analyze therapeutic efficacy of PEIT on the postop patients who have recurrence tumor (diameter≤3cm and numbers≤3), we can get the results as following: 30 cases were effective and the efficiency rate was 88.24% of HCC (30/34), 17 cases were effective and the efficiency rate was 68% of ICC (17/25). Through Chi-square test, there have signification of statistics ( p<0.05). Conclusion (1) Different histio-pathology types of primary liver cancer have different ultrasound characteristics. The incidence on the left lobe of liver and the incidence rates on women patients is increasing , the boundary definition is decreasing by turns of HCC,mixed hepatic carcinoma and ICC。The echo intensity is increasing with the diameter of tumor increasing. HCC′s echo intensity is higher than ICC′s when their diameter is same .(2) The therapeutic efficacy of PEIT on the recurence tumor of postop patient of HCC is superior to ICC. It is correlative with the pathological characteristics of HCC and ICC. So other treating measure should be taken on the recurrence tumor of ICC to elevate its therapeutic efficacy.