Comparison Of TUVRP And TURP: A Meta Analysis

Objective: To evaluate effectiveness,safety of transurethral vaporization resection of prostate(TUVRP) and transurethral resection of prostate(TURP).Methods: we searched MEDLINE,OVID,The Cochrane Central Register of Controlled Trial and CMB. Manual retrieval and citation search were added. The data messages were extracted after evaluating the quality of internalized studies. RevMan4.2.2 software was used for meta-analysis. According to the result of homogeneity test , we decided which model would be used, fixed effects model or random effects model. Publication bias evaluation was carried out.Results: fourteen RCTs including a total of 1401 patients met the inclusion criteria for the meta-analysis. All including literature was high-quality. There was no statistical significance between TUVRP and TURP on mean operating time, WMD=-2.39 minutes ,95% CI (-6.78,2.00),Z=1.07(p=0.29>0.05); The mean hospital stay, catheterization time, transfusion and intraoperative irrigant requirement were significantly shorter in the TUVRP than in the TURP group; there were no significant differences between TUVRP and TURP on incontinence, impotence and retrograde ejaculation; there was no significant differences between TUVRP and TURP on IPSS,Qmax and. No significant publication bias was found.Conclusion: Evidences indicated that TUVRP was much better than TURP on reduce bleeding,hospital stay and catheterization time. But there was no significant difference between two groups on curative effect, complication and operating time. Consequently TUVRP was equal effectiveness and safety to TURP. On some aspect, TUVRP was better than TURP. But we need to include in more high quality studies with compact designs and scientific method, in order to strengthen the argument.