Observe The Therapeutic Effect That Kangmai Capsula Mollis Treats â…  Or â…¡ Stage Of Diabetic Foot And Study IT On The Impact Of Serum CRP, MMP-9, IL-6

Diabetic Foot(Diabetic foot,referred to as DF) in patients with diabetes in a foot and nerve damage,blood vessels,skin,tendon,bone,and often leads to acral gangrene in chronic progressive disease,the disease-prone in the physical extremity,also known as acral gangrene.The disease is serious chronic complications of diabetes,one of non-traumatic amputation of the main reasons,which in Chinese medicine,"Wasting-thirst","mortification" and other areas,the incidence increased significantly in recent years,due to the rapid progression of the disease difficult to control,multi-to amputation or death,a great impact on the social productivity and quality of life of patients,it has been a general emphasis on the domestic scholars.Kangmai capsula mollis,is a soft capsule vein Professor Li Linggen clinical and scientific research over the years of research results,by Kangmai Capsule evolved,in the treatment of diabetic foot,such as peripheral vascular disease with good results.In this study,randomly selected in line with the diagnostic criteria of diabetic foot 60 patients aged 40-80 for the study,comprehensive analysis and evaluation of the capsula mollis in the treatment of diabetic foot capsules of efficacy,to study their impact on inflammation of the relevant factors,to further explore diabetes adequate pathogenesis,clinical treatment for the DF to provide new ideas and methods.Methods:A random number table 60 patients were randomly divided into two groups,and culture in soft gelatin capsules for the treatment of vein group(30 cases),Tongsaimai tablets for the control group(30 cases) observed before and after treatment in patients with symptoms,signs,blood lipids,blood rheology,serum C-reactive protein(CRP),Matrix metalloproteinase-9(MMP-9),interleukin-6(IL-6),the ratio of ankle-brachial(ABI),Transcutaneous oxygen pressure(T_cPO2),dorsal skin temperature changes in a series of indicators.Results:Soft Capsule Culture vein can significantly improve the relevance of patients with symptoms,signs,blood lipids,blood rheology,ankle-brachial ratio,T_cPO2, dorsal skin temperature performance,lower in patients with serum CRP,IL-6, MMP-9 inflammatory indicators,and are better than the control group(P＜0.01,P＜0.05).Conclusion:Kangmai capsula mollis has anti- inflammatory soft capsules,accommodate blood-fat,defibrase,the role of anticoagulation,can inhibit the occurrence of diabetic foot patients with the development of diabetic foot with a better therapeutic effect and to further validate the inflammation in the diabetic foot the occurrence and development played an important role in diabetic foot disease is an inflammatory response.