The Relationship Between Amniotic Fluid Volume After Preterm Premature Rupture Of The Membranes And The Maternal-Fetal Outcome

Objective: To determine the relationship between the residue amniotic fluid volume after PPROM and maternal-fetal prognosis.Methods: 145 PPROM patients of pregnancy between 28-34 weeks were collected. Patients were devided into three groups according to the residue Amniotic fluid index(AFI): AFI<50mm; 50mm≤AFI < 80mm; 80mm≤AFI<180mm. The general information,the rates of intra-amniotic infection(IAI),cesarean section and placental abruption; neonatal weight,rates of fetal distress,neonatal asphyxia,early-onset neonatal sepsis,neonatal aspiration pneumonia,neonatal respiratory distress syndrome (NRDS),neonatal jaundice,neonatal hypoglycemia,neonatal hypoxic-ischemic encephalopathy (HIE),neonatal respiratory failure (RF) and neonatal intraventricular hemorrhage (IVH) among the three groups were compared.Results: The differences of patient's age,gravidity and parity,white blood cell count(WBC),time of rupture of membrane,neonatal birth weight,rates of placental abruption,neonatal jaundice,neonatal hypoglycemia,NRDS,neonatal HIE and neonatal RF among the three groups were not significant(P>0.05). Among the three groups, the group which AFI<50mm had a shorter incubation period(P<0.05),and higher rates of cesarean section(69.44%),IAI(36.11%),early-onset neonatal sepsis(27.78%),neonatal aspiration pneumonia(88.89%),fetal distress(16.67%),neonatal asphyxia(27.78%) and hypoxic-ischemic myocardial injury(55.56%) (P<0.01). Logistic regression analysis showed that oligohydramnios might be an independent risk factor of intra-amniotic infection and early-onset neonatal sepsis.Conclusion: The shorted the incubation period, the increased the rates of cesarean section, clinical IAI, fetal distress, neonatal asphyxia, early-onset neonatal sepsis, neonatal aspiration pneumonia and neonatal hypoxic-ischemic myocardial injury might be concerned with oligohydramnios after PPROM,which could be used to monitor the safety of mothers and infants,and indicate the treatments.