The Clinical Research Of Warming-Invigorating The Kidney And Dispelling Cold, Dredging The Collaterals By Resolving Damp For Treatment Of Kidney-Asthenia Cold-Dampness Of Ankylosing Spondylitis

ObjectiveThis research is for the purpose of discussing warming-invigorating the kidney and dispelling cold,dredging the collaterals by resolving damp for treatment of kidney-asthenia cold-dampness of ankylosing spondylitis the clinical effectiveness, the drug safty and the adverse effects.By setting the control group,crosswise comparing on the effectiveness by contrasting with the treatment group in order to explore the Chinese medicine in treating the ankylosing spondylitis safely and effectively.MethodConforming to the ankylosing spondylitis kidney-asthenia cold-dampness patients who 60 examples integrates the standard to divide into two groups stochastically, the treatment group of 30 examples, gives conventional treatment +sulfasalazine 0.5g tid+ the decoctum of warming-invigorating the kidney and dispelling cold,dredging the collaterals by resolving damp; The control group of 30 examples, give conventional treatment + sulfasalazine 0.5g tid, formulation observation table, through patient symptom improved situation, BASDAI, BASFI grading and to routine blood test, ESR, CRP, IgG and so on determination, comprehensive appraisal this method of treatme-nt clinical curative effect, untoward effect and so on.ResultThrough to 30 example patients of 12 week-long observations, warming-invigorating the kidney and dispelling cold,dredging the collaterals by resolving damp to improve the patient's symptom, can reduce the patients waist and back pain, the early morning to be stiff obviously, the spinal column activity is limited and so on, improves patient's quality of life, and can reduce BASDAI, the BASFI integral obviously, although the symptom change compares not obvious difference with the control group (P>0.05), but BASDAI, the BASFI integral and the control group comparing the curative effect difference to have statistics significance (P<0.05).ConclusionWarming-invigorating the kidney and dispelling cold,dredging the collaterals by resolving damp for treatment of kidney-asthenia cold-dampness of ankylosing spondylitis, regardless of improving the patient symptom, enhanceing life , reduceing the disease activity to have the good curative effect, and the adverse effect and the side-effect, which has certain utilization prospect.