Objective: In this study,we used the method of tonifying kidney and warming DU-meridian in combination with acupotomy to treat the Ankylosing Spondylitis patients of kidney deficiency and DU-meridian cold.The changes of the laboratory indexes,efficacy evaluation indexes and TCM syndrome score were observed before and after treatment,so as to confirm the effectiveness and safety of tonifying kidney and warming DU-meridian in combination with acupotomy in relieving the clinical symptoms,improving related efficacy indexes and pain degree of patients with Ankylosing Spondylitis of kidney deficiency and DU-meridian cold.It provides effective methods and approaches for the treatment of this disease.Methods: Sixty patients who were consistent with the research criteria of Ankylosing Spondylitis of kidney deficiency and DU-meridian cold were selected and randomly divided into treatment group and control group,with30 cases in each group.Control group was treated with leflunomide tablets10 mg bidpo.Patients in the treatment group were given 10 mg leflunomide tablets bidpo treatment,and on this basis were given the Bushen-Wendu formula(300ml a day,warm administration after breakfast and dinner,150 ml a time)and combined with acupotomy for release and adhesion treatment that designed by my tutor based on years of clinical experience.The acupotomy treatment was performed once every 7 days,and the treatment course of both groups was 8 weeks.By comparing the changes of the laboratory indicators(CRPăESR),TCM syndrome score,patient global assessment(PGA)score and efficacy indicators(pain VAS score,BASFI score,BASDAI score)before and after treatment,SPSS26.0 statistical software was used to analyze and process the collected data.Thus to evaluate the therapeutic effect of tonifying kidney and warming DU-meridian method combined with acupotomy on Ankylosing Spondylitis patients of kidney deficiency and DU-meridian cold.Results: 1.Comparison of main symptoms of traditional Chinese medicine: After treatment,the improvement of lumbosacral pain,back pain,restriction of lumbar activity and morning stiffness in the treatment group was significantly better than that in the control group,with statistical significance(P < 0.05).2.Comparison of therapeutic indexes: After treatment,PGA score,pain VAS score,BASDAI score and BASFI score were decreased,and the treatment group was significantly better than the control group,with statis tical difference(P < 0.05)3.Comparison of biochemical indexes: After treatment,the reduction level of CRP and ESR indexes in the treatment group was significantly better than that in the control group,with statistical significance(P < 0.05).4.Comparison of overall effective rate: The total effective rate after treatment was 93.10% in the treatment group,and 75.00% in the control group.The treatment group was superior to the control group,with statistical significance(P < 0.05).5.No adverse events were observed in both the treatment group and the control group during the treatment.Conclusion: 1.The combination of tonifying kidney and warming DUmeridian combined with acupotomy can significantly reduce the TCM syndrome score of patients with kidney deficiency and cold deficiency type hunchback,and improve the clinical symptoms of patients.2.The combination of tonifying kidney and warming DU-meridian combined with acupotomy can significantly reduce the PGA score,VAS score,BASFI score and BASDAI score of patients with hunchback of kidney deficiency and cold deficiency,and the standard reaching rate of ASAS20 is significantly improved.3.The laboratory indexes ESR and CRP levels of patients with kidney deficiency and cold deficiency type hunchback can be effectively controlled by tonifying kidney and warming DU-meridian and regulating body function combined with acupotomy.Effective control of inflammation in the body.4.Tonifying kidney and warming DU-meridian combined with acupotomy has better safety and no obvious adverse reactions. |