The Case-control Study Of The Large Intestinal Polyps' Risk Factors

Objective:Investigated the risk factors of large intestinal polyp, which could provide a scientific basis for monitoring and precaution the occurrence of the large intestinal polyps.Methods:Patients who would be accepted electronic colonoscopy or large intestinal polypectomy at the Qi-Lu hospital of Shangdong University were investigated with an uniform questionnaire, and then they were divided into control group (150 cases) and polyp group (216 cases) according to the result of the electronic colonoscopy. The results of investigation were analyzed with t orχ2 test, and then were analyzed with univariate analysis and multivariate analysis by non-conditional Logistic regression analysis.Result:Compared with the control group, patients of polyps group had higher body mass index, higher education level, and the difference had statistically significant (respectively P<0.02; P<0.001). Smoking and drinking, mainly engaging in intellectual work and not always concerned about the health-care knowledge have more chance to catch the large intestinal polyps than non-smoking and drinking, mainly engaging in physical-based work and regular attention to health-care knowledge, which differences have statistically significant (respectively, P< 0.02; P< 0.001; P< 0.05). Compared with the control group, patients were often have breakfast, partial eating salty foods, expending more than 30 minutes when dining, meals interval (more than 6 hours or less than 4 hours), bedtime at night (more than 8 hours or less than 5 hours) were higher in polyps group, and those differences have statistically significant (respectively, P<0.001; P<0.01; P<0.01; P<0.001; P<0.001). the frequency of pork ingested per-week, the frequency of animal protein ingested per-week in polyps group were higher than the control group, and the differences have statistically significant(respectively, P=<0.02; P< 0.001). While the frequency of milk and its products ingested per-week, eggs'intake frequency per-week, vegetables'ingested frequency per-week in polyp group had differences with the control group (respectively, P<0.01; P<0.001; P<0.001). But starch intake frequency per week, frequency of fruit ingested weekly and often or daily feeling anxiety in polyps group had no significant difference with the control group (respectively, P= 0.99; P= 0.651; P= 0.34). Analyzed by logistic regression, those data show that educational levels (senior high school and further than senior high school), smoking and alcohol consumption, daily or regularly have breakfast, likes to eat greasy foods, meals interval (less than 4 hours or more than 6 hours) were risk factors for the large intestinal polyps, the OR values respectively were 3.491,7.381,8.248,5.572,7.516; and often concerning about the knowledge of health was a protective factor of the large intestinal polyps, OR value was 0.345; career (mainly brain-based), likes partial salty foods, expending more than 30 minutes when dining, animal protein's ingest frequencies per-week, the frequencies of egg intake per-week, vegetables'ingest frequencies per-week had no significantly correlation with the occurrence of the large intestinal polyps.Conclusion:The occurrence of the large intestinal polyps had correlation with the diet, smoking and drinking and eating habits, while paying attention to the knowledge of health is a protective factor of the large intestinal polyps. body mass index, career (mainly brain-based), likes partial salty foods, expending more than 30 minutes when dining, animal protein's intake frequencies, the frequencies of egg intake, vegetables'intake frequencies had no significantly correlation with the occurrence of the large intestinal polyps.