Analysis Of The Clinical Features And The Relevant Factors Impacting To Short-Term Effection Among 50 Children With Status Epilepticus

Objective: To study the clinical features and the relevant factors impacting the short-term effects among 50 children with status epilepticus(SE).Methods: The medical records of 50 children with SE were collected, of which diagnosed in the First Affiliated Hospital of Guangxi Medical University from June 1999 to April 2009, and were analysised retrospectively the relevant factors included: age of onset,cause of disease,predisposing cause,seizure type,duration and controlling time. And found the relation between these factors and the short-term effects.Results: In this group , 1. The age of onset of SE varied from half a month to 18 years old, the average age was 5 years old. The children older than 3 years old and younger or equal to 3 years old were made up with 50% respectivly.2. The cause of 50 diseases included: symptomatic SE(N=68%), idiopathic SE(N=24%), febrile convulsion of SE(N=8%).3. Induced by infection(N=62%), among them, 29 children had respiratory tract infection, 2 children had diarrhea disease. Induced by disabling anti-epileptic drugs(AEDs)(N=20%). No predisposing causes(N=8%).4. CSE was made up with 86%, included, GTCS(38 cases), TSE(3 cases) and MSE(2 cases). NCSE was made up with 14%, included, ASE(4 cases), CPSE(3 cases).5. The shortest duration was 10 minutes, the longest duration was 2 days(average 2h), included, 60 minutes or less(N=80%), more than 60 minutes(N=20%).6. The shortest controlling time was 4 minutes, the longest controlling time was 18 days(average 9h), included, 30 minutes or less (N=84%), more than 30 minutes(N=16%).Conclusions: 1. SE can be often seen in all age groups, and more common over the age of 5,however, symptomatic SE, infection, CSE was most common. 2. The effective rate with SE was 92%, the mortality was 2.2%, the neurological sequela was 13%. The short-term effects of SE were closely related to the duration and controlling time. SE lasted 60 minutes or less and controled 30 minutes or less had the better treatment outcomes.