From Blood Stasis Endometriosis Systemtic Evaluation Of Pain

Purpose: Systems analysis from the stasis of endometriosis pain treatment safety and effectiveness, in order to make objective and reliable evaluation of TCM treatment for the selection of patients and clinicians to provide the best currently available evidence to help clinical decision making, and provide a basis for further research and laid the foundation.Method: Use of evidence-based medicine (EBM) approach, a comprehensive search of domestic Chinese medicine treatment of endometriosis pain clinical research literature into treatment from the stasis of the pain of endometriosis patients randomized study of clinical observation of included studies, literature and methodological quality (including random method, blinding, allocation concealment and lost) evaluation of statistical software with Revman4.3 descriptive quantitative analysis or qualitative analysis.Results: Total of 19 research articles, including 1615 cases of clinical randomized controlled study. Statistics show that from stasis treatment of endometriosis pain with conventional western medicine treatment group compared with the control group markedly significant, Traditional Herbs in the treatment of endometriosis pain and side effects clear. Meta-analysis showed that: the treatment group and control group, the total efficiency of OR = 2.38,95% CI﹝ 1.53,3.68﹞ ,P = 0.0001; dysmenorrhea remission OR = 2.48,95% CI﹝ 1.75,3.52﹞ ,P <0.00001 ; pelvic pain remission rate OR = 3.49,95% CI﹝ 1.64,7.41﹞ ,P = 0.001; anus fall rate of pain relief OR = 3.76,95% CI﹝ 1.17,12.09﹞ ,P = 0.03; recurrence OR = 0.21, 95%CI﹝0.12,0.36﹞, P <0.0001, Chinese group than the control group. Intercourse pain remission rate OR = 1.83,95% CI﹝ 0.80,4.17﹞ ,P = 0.15; cysts reduced rate OR = 1.98,95% CI﹝ 0.74,5.31﹞ ,P = 0.18; tender nodular remission rate OR = 1.27,95% CI﹝ 0.65,2.50﹞ ,P = 0.48, effect of treating group with the control group fairly. CA125 and sex hormones on the level of descriptive qualitative analysis of efficacy of traditional Chinese medicine group and western medicine quite. 12 studies reported on adverse reactions observed a low incidence of adverse reactions in Chinese medicine.Conclusion: From Blood Stasis endometriosis pain is a kind of effective clinical method of less adverse reactions, but the incorporation of quality literature not ideal, there are some publication bias, in terms of efficacy and safety aspects need randomized, double-blind, multicenter, large sample of high-quality clinical trials to be further confirmed.