| Purpose and BackgroudUlcerative colitis is a chronic nonspecific inflammatory disease of rectum and colon without the distinct etiological factor which involves intestinal mucosa and stratum submucosum that the rectum and sigmoid colon are mainly suffered。The major clinical symptom is abdominal pain, diarrhea, bloody purulent stool。The pathogenesis of UC is not clear up to now, which is concerned with environment, inheritance, infection and immunity。The treatment of the modern medicine is limited for its nonspecificity, great adverse reaction, symptom recurrent attacks or worsens when drugs not taken that affects the living quality of UC patients。So we need to search the more effective drugs with little adverse reaction or a new treatment。Ulcerative colitis by means of active disease stage, remission two。Especially in the treatment of active ulcerative colitis difficult, many current Western medicine treatment to hormone and immune inhibitors, salicylic acid-based agents, but the toxic side effects of these drugs, long-term use can cause liver and kidney damage。Therefore, how to control active UC, a large number of domestic and foreign experts。Western medicine has no effective therapy for treating the disease, while the medical treatment of the disease showed significant efficacy advantages。After a long exploration of clinical practice instructors and lessons learned, the use of Lichangtang, Tripterygium glycosides tablet and ulcers spiritual enema with active ulcerative colitis with the exact efficacy and decreased side effects。The purpose of this study is to observe the management of intestinal soup, Tripterygium glycosides tablet and ulcers spiritual enema with active ulcerative colitis patients。 MethodAll 80 Subjects were all from July 2008 to July 2010 during the Chinese medicine hospital in Shenzhen City, spleen and stomach diseases clinics and medical wards (with active ulcerative colitis) patients, single-blind randomized groups, according to the order of patients to the yard, corresponding to a random number for each patient, the treatment group into odd (ie, management of intestinal soup, Tripterygium glycosides tablet and ulcers spiritual enema), and even into the control group (SASP) group。Two groups were 1 month to 1 course of treatment were evaluated after 2 courses of treatment。Eefore and after treatment were performed colonoscopy and histopathological examination, before and after treatment in patients with symptoms and signs and the endoscopic mucosal repair under the circumstances, and then use the results of statistical analysis software。Result1,The two groups of patients to statistics by the statistical test, P> 0.05, no significant statistical difference between the two groups, so there are comparable。2,After the treatment, the total curative effect of the treatment group is95%, and the control group is 62.5%。The statistic analysia reveals when P<0.05, it has significant differences。3,In the main symptoms, treatment and control group (diarrhea, pus and blood stools, abdominal pain) rates were 90.90%,60%,91.43%,78.13%, 84.62%,63.64%, the treatment group than in the control group; Above grouping statistics P<0.05, show that the effect of each group and the control group had significant differences。4,The efficacy of colonoscopy and remission, the treatment group, the effective rate was 87.5% and 60%; DAI score grading efficacy in the treatment group in the light condition, in severe total effective rate was 93.33%,87.5%,88.89%, than the control group, mild, moderate, severe total effective rate。Compared with the control group, two groups were statistically significant (P<0.05)。5,In the side effects, side effects of the treatment group had significantly less than the control group。 less than the control group。ConclusionLichangtang, Tripterygium glycosides tablet plus ulcer spiritual enema for ulcerative colitis treatment of active clinical effect is obvious and better than sulfasalazine drug side effects compared with the western medicine, Chinese medicine in the treatment showing the Significant disease-specific, and in improving the quality of life has great advantages。At the same time, "Li Ling Chang Decoction enema oral treatment with ulcers, Tripterygium glycosides tablet" for the Chinese medicine treatment of active ulcerative colitis and provides a new treatment methods and thinking。... |
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