Ultrasound-guided Percutaneous Minimally Invasive Biopsy In The Diagnosis Of Chronic Lymphocytic Thyroiditis And The Clinical Significance

BackgroundThe incidents of Lymphocytic thyroiditis (H ashimolo s thyroiditis, HT) increased each year. The clinical symptoms of HT are atypical,the common complains are neck mass and hyperthyroidism performance, which cause the result of misdiagnosis and unnecessary surgery treatment. Doctors became pay attention on TC in combination with HT because of the increased incidence in recent years. Currently, clinical diagnose relies on the preoperative fine needle aspiration biopsy and the color Doppler ultrasound. However, the amount of cell sample which come from the aspiration biopsy is insufficient. But the pathologic diagnosis of the disease above is in highly demanding, at the same time the sensitivity and specificity is variable. On the other hand, the preoperative diagnosis of thyroid cancer was low, because its variability in real background of ultrasound. The coincidence of the color Doppler and clinical diagnosis of HT was low. Thyroid biopsy (CNB), is simple, safe, less complications and the advantages of high accuracy. The use of CNB can reduce the excessive surgery of Benign nodules and provide a ample basis for sufficient diagnosis. This article aims to explore the CNB in the diagnosis of the clinical significance of HT.ObjectiveUltrasound-guided Percutaneous minimally invasive biopsy in the diagnosis of chronic lymphocytic thyroiditis and the clinical significance MethodsReview 92 patients from January 2009 to December 2009 who diagnosed thyroiditis and thyroiditis with thyroid nodules through biopsy in our hospital. The diagnosis, treatment and the follow-up results were analyzed.ResultsDerived satisfaction biopsy in 92 patients, puncture success rate was 100%. Biopsy diagnosis of chronic lymphocytic thyroiditis in 32 cases, combined with chronic lymphocytic thyroiditis in 20 cases of nodular goiter, chronic lymphocytic thyroiditis with thyroid cancer, 40 cases. 49 patients underwent surgical biopsy and pathology consistent with rate of 97.96%. 1 case of false negative and false-negative rate of 2.04%, no false positive. The patients, get the diagnosis of chronic lymphocytic thyroiditis and chronic lymphocytic thyroiditis combined with nodular goiter, underwent the anti thyroid treatment. follow-up study showed that the thyroid ultrasonography and thyroid function tests of the above 92 patients got varying degrees of improvement targets. All the patients have not hot adverse reactions and complications during the puncture process.ConclusionUltrasound-guided thyroid biopsy diagnosis of thyroiditis have confirmed meaning, which makes up the limitations which relying on imaging and the check of thyroid autoantibodies. The diagnostic accordance rate of thyroiditis combined with thyroid cancer was improved and the rate of the benign nodules excessive operation is reduced. To sum up, Ultrasound-guided thyroid biopsy is an accurate, safe and simple method of diagnosis of thyroiditis, which provides a sufficient basis for proper treatment.