| Objective:The traditional method is Guided Tissue Regeneration(GTR)combined with bone grafting,but the traditional barrier membrane materials have poor ability to promote tissue regeneration.Traditional GTR surgery in the trauma,heavy postoperative response,gingival recession is more obvious.This study innovatively applies Minimally Invasive Surgical Technique(MIST)and CGF barrier membrane jointly to periodontal tissue regeneration,and evaluates its clinical efficacy through clinical and CBCT indexes,providing reference programs for the clinical treatment of periodontitis.Method: The study period was from September 2021 to July 2022.Subjects were selected from patients receiving periodontal treatment in Hefei Stomatological Hospital,and 29 patients were enrolled.Randomly divided into 2 groups using a random number table,the experimental group of 14 cases,including 4 males and 10 females,was treated with MIST combined with CGF barrier membrane(covering CGF membrane in bone defect area).In the control group,15 patients,including 5males and 10 females,were treated with GTR(covering collagen membrane in bone defect area).The experimental group was(33.36±7.88)years old,and the control group was(35.87±11.06)years old.There was no significant difference in gender distribution and age between the two groups(p>0.05),which could be compared.The clinical and CBCT indexes before and 6 months after the operation were compared between the two groups.A follow-up visit was performed at 2 and 4 days after surgery using Visual Analogue Scale(VAS)to assess the pain and swelling in the operative area.SPSS26.0 was used for data analysis.Measurement data conforming to normal distribution were expressed as mean ± standard deviation((?)±s).Independent samplet test was used to compare the depth of probing,gingival recession,clinical attachment loss and bone defect before and 6 months after surgery between the two groups.Paired sample t test was used to compare the changes of probing depth,gingival retreat depth,clinical attachment loss and bone defect depth DB of CBCT in each group before and 6 months after surgery.Independent sample t test was used to compare postoperative pain and swelling.By x2 test,the difference was statistically significant when p<0.05.Results: Before surgery,the experimental group and the control group were compared in various indexes(PD,CAL,RD,DB),and there was no statistical significance(p>0.05),suggesting that the comparison between the two groups was feasible.Six months after surgery,PD decreased from(6.36±1.69)mm to(3.07±0.73)mm,CAL decreased from(8.29±1.85)mm to(5.50±1.06)mm.In the control group,PD decreased from(6.47±1.51)mm to(3.30±0.70)mm,and CAL decreased from(8.37±1.84)mm to(6.40±1.49)mm.There were significant differences in PD and CAL between the two groups compared with those before surgery(p<0.001).There was no significant difference in PD and CAL between groups(p > 0.05).6 months after surgery,gingival recession of different degrees was observed in both groups after surgery,and the difference was statistically significant compared with preoperative(p<0.001).The RD of experimental group increased from(1.93±0.65)mm to(2.43±0.76)mm,and that of control group increased from(1.90±0.85)mm to(3.17±0.99)mm.Six months after surgery,both groups achieved good bone mass increase on CBCT,with statistically significant differences compared with preoperative results(p<0.001).There was no significant difference between groups(p>0.05).The bone defect depth of the experimental group was reduced from(7.20±1.86)mm to(3.76±1.25)mm,and that of the control group was reduced from(7.04±1.23)mm to(3.88±1.33)mm.The VAS score of the experimental group was lower than that of the control group on the second day after surgery,and the difference was statistically significant(p<0.05).There was no significant difference in pain VAS score on day 2 and day 4after surgery and swelling VAS score on day 4 after surgery(p>0.05).Conclusions: MIST combined with CGF barrier membrane can significantly reduce the depth of exploration of teeth with vertical bone defect,reduce the degree of clinical attachment loss,have good bone regeneration ability,obtain less gum retraction,and reduce postoperative swelling discomfort in patients. |
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