| ObjectivesUlcerative colitis is a chronic non-specific inflammatory in the rectum and colon and the cause is not very clear. Lesions are limited to the mucosa and submucosa.The clinical manifestations are diarrhea, pus and mucusstools, abdominal pain. Severity ranging from it is a chronic recurrent process mostly. Because the cause is unknown. The existing treatment methods are used in conjunction with patients in longer time. They impact patients of mental, development, nutrition and so on.The disease is difficult to cure, has are relapse rate and certain cancer rates.It is one of the modern difficult medical treatment by the World Health Organization. By the modern Chinese literature is reviewed, including etiology and pathogenesis, syndrome differentiation, treatment, etc.It has a certain features and advantages but the lack of specificity. It is meaning that further excavation is used to guide doctors to treat diseases better. MethodsSearch the past five years (2005.1-2010.5)《Chinese Biomedical Literature Database(CBM)》,《VIP Chinese Science and Technology Academic Journal》involving aspects of ulcerative colitis in Chinese literature.Screen documents according to inclusion, exclusion criteria and eatabish Chinese medical literature information database by etiology, pathogenesis, syndrome differentiation and treatment and find the discipline, On traditional Chinese medicine and oral mesalazine in ulcerative colitis have a Meta-analysis and find the conclusion.Result The simple deficiency (spleen, kideney) and empirical (wet, heat, blood stasis) are discussed seldom in literature in terms of etiology and pathogenesis. The actual situation mixed is more common. It shows the complexity of the disease pathogenesis; The syndromes have the partakersⅡ,Ⅱ,Ⅳ,Ⅴ-type, six types, seven types. They are reflected in the medicine of thesoul---diagnosis and treatment, which damp in the dominant, a few mentioned stages of the organs of governance and administration and have achieved good results. Most of the documents referred to treatment, variety, have achieved good effects. Screen 345 randomized controlled documents and select from oral treatment of Chinese medicine in the treatment group and control group with oral mesalazine the literature treatment of ulcerative colitis, a total of eight in the Meta-analysis. The total odds ratio of Clinical effective of treatment group (OR)= 3.71,95% confidence interval (CI) was 2.26-6.10. The diamond is in the right side of the middle line, the Z test, Z= 5.19, P<0.00001, the difference was very significant that the treatment groups are better than mesalazine tablets in the Chinical effective. In the "funnel" icon analysis, graphics basic is symmetry, it is considered the existence of publication bias is small. ConclusionThe most scholars believe that the etiology and pathogenesis of the actual situation based mixture, of which the spleen, heat, blood stasis in the majority, and many scholars refer to the pathogenesis of drug through literature review of modern medicine. Four types are the main in syndrome type, but the damp and spleen deficiency are the dominant, followed by liver depression and spleen, but most of the scholars mentioned type of Qi stagnation, a consensus has not been mentioned in traditional Chinese medicine clinics. From the treatment, detoxification can be seen starting from the current focus of the study.8 documents are randomly selected from the literature. Current available information is supporting the Chinese treatment of clinical efficacy in patients with ulcerative colitis is superior to mesalazine tablets. |
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