Analysis Of The Duodenogastric Reflux Of GERD Patients

Object: To detection the duodenogastric reflux of GERD patients by Color Doppler Ultrasonography and to analyze the ralationship between the duodenogastric reflux and the severity of GERD. To investigate the role of the duodenogastric reflux in the pathogenesis of GERD and devolop a simple,noninvasive and nonradiative method for evaluating duodenogastric reflux.Materials and Methods: Eighty-two GERD patients were collected. To divided patients into NERD group and RE group according to the results of endoscopy, then divided them into four groups in accordance with symptom socres. Thirty-three cases without symptom of gastroesophageal reflux disease were served as control. Detection the duodenogastric refluxof all GERD patients and asymptomatic healthy volunteers by Color Doppler Ultrasonography and then analyze data.Results: 1. Diagnostic rate of Color Doppler Ultrasonography for the duodeno-gastric reflux was 97.39%. 2. The frequency of DGR, the mean distance of color signal from the pylorus and the reflux index in patients with gastroesophageal reflux disease were all more than healthy volunteers (P<0.001). 3. The frequency of DGR, the mean distance of color signal from the pylorus and the reflux index in RE patients were all serious than NERD patients (P<0.05). 4. DGR in patients had no relativity with the severity of GERD (P>0.05).Conclusion: 1. The Color Doppler Ultrasonography has some value for the duod-enogastric reflux. 2. DGR has some value in the pathogenesis of GERD. 3. DGR has some value in the pathogenesis of RE. 4. DGR has no effect on the severity of GERD.