The Study Of Low Flow Sevoflurane Target-controlled Inhalational Anesthesia

Objective:To observe the clinic regulation and the change of hemodynamic in Sevoflurane low flow target-controlled Inhalational anesthesia, and explore the quantitative indicators of medicine under the target controll.Methods:sixty adult Patients scheduled to undergo surgery were devided into two groups randomly:Sevoflurane group(S group) and propofol group (P group). All the patients of P group were injected propofol intravenously; low flow Sevoflurane target-controlled Inhalational anesthesia used to S group (BIS is 40). Recorded the changes of MBP,HR in pre-induced(T1)and After the traceal intubation 3 (T2),15 (T3),30 (T4) 45 (T5),60 (T6),90 (T7),120 (T8) min respectively; excepting that the S group recore the MAC of Sevoflurane'IT,ET at the same time.Results:MBP of statistical difference was observed between T2 and T1 (P<0.05),P group and S group respectively (P<0.05);there is no statistical difference compare T3 with T7 (P> 0.05); ET is 2.46, MAC is 1.4. Conclusions:the change of hemodynamic induced by Sevoflurane is light than intravenously, the maintenances of low flow Sevoflurane target-controlled Inhalational anesthesia is stable,convenient and efficient.