A Clinical Evaluation Of Therapeutic Efficacy Of Endovascular Therapy For Arteriosclerosis Obliterans

Methods:From January 2007 to January 2010,142 arteries in 138 patients diagnosed with ASO were treated by endovascular therapy. All analysis was performed according to the medical history and follow-up data of these patient. The technical success rate, clinical success rate, the incidence of complication and the mortality rate were reported after assessing the perioperative risk factors, clinical classification, results of assistant examination and operation documents. Patients were classified based on symptoms, TASC Classification and lesions of trifurcation below the knee for the purpose to observe the cumulative primary patency rate, limb salvage rate and survival rate of different periods. Meanwhile, the impact of risk factors on postoperative patency was evaluated.Results:The technical success rate of endovascular treatment for patients with femoropopliteal lesions (142 affected limbs of 138 patients) was 95.77%(136/142). Perioperative complication rate was 17.61%(25/142) and mortality was 2.17%(3/138).128 limbs gained improvement with different degree and the clinical success rate was 90.14%(128/142).The cumulative primary patency rates of 3,6,12,24 months after operation were 96.64%,88.36%,64.69% and 38.82% respectively. The limb salvage rates of 1 year and 2 year after operation were both 95.07%(135/142), with a survival rate of 96.38% (133/138)Conclusions:with its satisfying mid-short-term efficacy and limb salvage rate, endovascular therapy is a feasible, safe, and effective procedure for the treatment of ASO. from clinical data evaluated, it can be concluded that symptoms, TASC Classification and lesions of trifurcation below the knee all have an impact on the primary patency rate with different degrees. However, factors such as diabetes, heart disease, cerebrovascular disease, smoking, have no significant relevance to the primary patency rate.