The Advanced Research Of Subclinical Hyperthyroidism

Subclinical hyperthyroidism is a special kind of hyperthyroidism, as defined by the presence of a low serum TSH level in the face of normal serum free T4 and free T3 levels. According to etiology, it can be divided into two types of endogenous and exogenous subclinical hyperthyroidism. Nodular goiter, the potential Graves disease, thyroiditis, and intake of excessive amount of L-T4 is the common cause of it. Most symptoms of subclinical hyperthyroidism are not obvious, but the heart and autonomic nervous dysfunction can occur early; the incidence of auricular fibrillation raises up; subclinical hyperthyroidism increases risk of osteoporosis in post-menopausal women patients. The diagnosis should be excluded from the disease caused by a temporary reduction in TSH of other causes. The treatment of subclinical hyperthyroidism should be weighed. If there is a noticeable reduction of TSH, we can give the homologous treatment. If TSH has a mild reduction, we should follow up regularly. Klinefelter's syndrome, characterised by a 47, XXY chromosomal pattern, has largely been associated with physical abnormalities. Here, we report a case of Klinefelter's syndrome in a 28-year-old man who had metabolic syndrome. We diagnosed him with Klinefelter's syndrome from his atrophic testicles, primary hypogonadism in hormonal examination, infertility, and a chromosomal aberration of 47, XXY. From the fat somatotypes, high level of blood glucose, blood fat and blood pressure, we diagnosed him with metabolic syndrome. In the end, we review some literatures about Klinefelter's syndrome and metabolic syndrome.