| Treating blood deficiency with Angelica Yin Zi and wind-dryness senile pruritus, through observation of its clinical efficacy, an objective assessment of Angelica sinensis Yin Zi Treating senile pruritus (blood deficiency and wind-dryness) in the clinical efficacy, and to explore the mechanism of its efficacy, in order to further promotion of Chinese medicine combined basis for the treatment of skin itching disease.All self-Hospital Of this study were from February 2008 to December 2009 in Hubei Province during the Chinese medicine hospital dermatology outpatient clinic patients, in line with the diagnostic criteria of skin pruritus in all patients who meet the diagnostic criteria, select a blood deficiency and wind-dryness as an object of study, a total of observed cases of 129 cases,129 cases selected randomly divided into two groups, treatment group 66, control group 63 cases, two groups of patients with sex, age, duration, illness, etc. no statistical significant difference (P> 0.05), comparable.Treatment group,66 cases:taking the classic side Treating Angelica Yin Zi, Prescription Composition:angelica 15g, Radix Rehmanniae 15g, Chuan Xiong 15g, white peony root 15g, Radix Astragali 20g, fleece-flower root 15g, Tribulus terrestris 15g, Nepeta 10g, wind 15g, Licorice 6g, cattle sub-10g, Chan Yi 6g, mint 6g. Dialectical Modified:frail elderly persons, reuse Astragalus, Codonopsis; itching worse, plus Scorpio, Digupi; lesions hypertrophy, Al Qaa glue, Salvia; night sleep soundly poor persons, Kaya Kodo, Suanzaoren, Albizia. Shuijianbi, first soaked in 0.5 hours with cold water, large Huo Jian open, slow fire boiling 20min, fried two times against the juice 300ml, sooner or later,2 minutes warm clothes,1 day 1 agent,4 weeks for a course of treatment. Control group,63 cases:oral dispersible tablets of cetirizine hydrochloride (Hei-ning) State medicine accurate H20040308 (Yichang Changjiang Pharmaceutical Ltd.) 10mg/tablets, a day before going to bed. Groups outside the hospital from the pharmaceutical drugs are urea cream, usage:twice a day, sooner or later coated with. Both sets of the total course of treatment for 4 weeks, observed a times a week.Efficacy Standard:cure:pruritus completely disappeared, the skin without skin lesions; markedly:itching significantly reduced without affecting the life and sleep, skin, leaving a small amount of scratches; valid:itching some relief, but sometimes it can still affect the life and sleep, but the with non-significant difference before treatment, the skin can be seen on the small piece of scratch; invalid:no significant improvement in symptoms such as itching. Before and after treatment were observed in patients with clinical symptoms and signs of improvement in the situation Situation, and make statistical processing, to compare their cure rate, markedly effective, and efficient.Note that the two groups during treatment in patients with records of adverse events, local skin changes, such as dry, scaling, scratches, etc., systemic symptoms such as vomiting, diarrhea, dizziness, drowsiness, so as to methods of this safety evaluation.All measurement data the data to mean±standard deviation ((?)±s), said measurement data with the t test, count data using X2 test.1. Clinical comparison:the treatment group cured 16 cases (24.2%) were cured,30 cases (45.5%), effective in 11 cases (16.7%), ineffective in 9 cases (13.6%), recurrence in 6 cases (9.1%) overall response rate 86.4%. Cured four cases of the control group (6.3%) were cured,25 cases (39.7%), effective in 13 cases (20.6%), ineffective in 21 cases (33.3%), recurrence in 16 cases (25.4%), the total effective rate 66.7%. Comparing the two groups The total effective rate (P<0.05), treatment group was more effective than the control group.2. Adverse reactions during treatment were compared in patients found no significant adverse reactions. Investigation before and after treatment of blood, urine, feces conventional and liver function, kidney function and found no abnormal changes.This topic using its comparative approach to traditional Chinese medicine Angelica sinensis Yin Zi plus or minus side to the treatment group, cetirizine HCl dispersible tablets for the control group B, respectively, were observed after treatment of clinical symptoms improve the situation, through the statistical processing, were a Conclusion:The traditional Chinese medicine Angelica sinensis Yin Zi side addition and subtraction can be effective treatment for pruritus of skin, its higher efficiency, the recurrence rate was significantly lower than the control group, and the clinical use of safe, non-obvious side effects, in order to further promote the traditional Chinese medicine pruritus provide some scientific basis. |
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