The Clinical Application Value Of MSCT With Image Post-processing Techniques In The Diagnosis Of Lung Cancer

Purpose: To investigate the clinical application value of MSCT with image post-processing techniques in lung cancer.Methods: Retrospective analysis the images of 81 cases with lung mass or nodule. The 81 cases were done with doing MSCT with image post-processing techniques, including multi-planar reformation (MPR), curved-planar reformation (CPR), minimum intensity projection (MinIP), maximum intensity projection (MIP), three-dimensional surface shaded display (SSD) and volume reproduction (VR). 65 cases were examined with CT virtual bronoscopy (CTVB).43 patients were examined with pulmonary three-dimensional CT angiography (CTA). Then 46 suspected central bronchogenic carcinoma cases were carried with bronchoscopy. This was statistically studied in diagnosis between 48 central bronchogenic carcinoma cases with MSCT image post-processing techniques and 46 central bronchogenic carcinoma cases with bronchoscopy. To compare the differences between the pure chest CT cross-sectional images and combined MSCT with image post-processing techniques images in the sensitivity, specificity, positive predict value, negative predict value and accuracy rates of imaging diagnostic results for 81 cases with pulmonary mass or nodule. To compare the statistically significant differences between the pure chest CT cross-sectional images and combined MSCT with image post-processing techniques images in the display rate of basic malignant signs for 15 cases with peripheral lung masses or nodules. To evaluate the clinical application value of MSCT with image post-processing techniques in the diagnosis of lung cancer.Results: The final confirmed result was 18 benign cases and 63 malignant cases. 63 malignant cases were confirmed by the bronchoscopy, CT-guided puncture or Surgery. There were central bronchogenic carcinoma in 48 cases and peripheral lung cancer in 15 cases. 63 cases with malignant lung masses or nodules, including squamous cell carcinoma in 32 cases, adenocarcinoma in 26 cases, small cell carcinoma in 4 cases and large cell carcinoma in 1 case. 42 males and 21 females. mean ages 64.5(37~82) years- old. The surgery sub-types of 48 central bronchogenic carcinoma cases were 5 cases with intraluminal nodular, 15 cases with circular stenosis and 28 cases with eccentric stenosis truncated. The imaging diagnostic results of MSCT with image post-processing techniques and the results of bronchoscopic with pathological were compared, the statistical conclusion was P>0.05. There were not significant differences between the two. The sensitivity, specificity, positive predict value, negative predict value and accuracy rates of imaging diagnostic results for pulmonary mass or nodule were 88.89%, 72.22%, 91.80%, 65.00%, 85.19% by solely using conventional CT cross-sectional images. The sensitivity, specificity, positive predict value, negative predict value and accuracy rates were 92.06%, 88.89%, 96.67%, 76.19%, 91.36% after jointing MSCT with image post-processing techniques. In the way of displying some malignant basic signs of 15 peripheral lung cancer cases, the statistical analysis result was P<0.05.So there were significant differences between conventional chest CT cross-sectional with jointing MSCT many image post-processing techniques and conventional chest CT cross-sectional images.Conclusion: MSCT with image post-processing techniques could evaluate degree and extent of the invaded trachea-bronchial tree by tumor. There was not significant difference between it and bronchoscopy, so the effection was the same. Secondly in the way of displaying many basic malignant signs of the lung cancer, the combination of chest CT cross-sectional images with MSCT image post-processing techniques was better, three-dimensional feeling was stronger, more look like real bronchoscope or surgical findings of the organizational structure than the conventional chest CT cross-sectional images. It could show some malignant signs, which were unclear or could not even be showed by conventional chest CT cross-sectional images. The accuracy of positive diagnosis to lung cancer was significantly improved. There's greater helpful to early detection and treatment of the lung cancer. Clearly the diagnosis of the combination of chest CT cross-sectional images with MSCT many image post-processing techniques were more convincing and better. In a word, using conventional chest CT cross-sectional images as the basis of imaging diagnosis, then jointing MSCT and many image post-processing techniques could significantly improve the diagnostic accuracy of the lung cancer. It could provide strong and true evidences in the preoperative stages of lung cancer, the choice of surgical treatment, the effection of treating and the monitoring of recurrenced tumor after operativing, and so on. There were great practical significance to discoverying the early lung cancer, and extensive application prospects both in clinical and study.