Epidemiological Investigation Of Alzheimer's Disease In Community Population In Hebei Province

Objective: To understand the distributed and epidemiological features of Alzheimer's disease in Hebei cities and coutries community-based old groups and its related factors. Provide the reference to establish preventioning measures to community aged dementia and elderly healthy care services . Methods: Using the stratified random sampling method, MMSE was used to evaluating senile dementia ,ADL was used to evaluat elderly people daily life, Hachinski distinguish dementia type. Useing DSM-IV and NINCDS/ADRDA standard to diagnostic AD and its subtype.Useing Unconditional multi-factor Logistic Regression analysis. Results: (1) 64.84% ,the total prevalence of chronic in those who were over 60 years old, including AD was a higher level, it increased with age ascendant trend. Located in the top five morbidity were: hypertension (32.35%), diabetes (11.37%), COPD(9.25%) , coronary heart disease (8.84%) and stroke (7.16%), AD located in the sixth, for 4.87%. (2)Among these 263 senile dementias,the prevalence of AD,VD,MD was 67.3%,1.57%,0.80%.Among these AD patients,severe\mediumand light type occupied 14.12%,67.79%,18.07%. (3 ) The prevalence of AD increases with age and the trend chi-square test (P﹤0.01), a statistical significance to learn, , The AD prevalence of female patients(5.90%) was higher than that of male ones (3.90%) , the difference was statistically significant.The oder of age ,the lower the degree of culture, the higher AD rates .by age 90 , the highest illiteracy rates above, for 54.85% group. (4)There are 11 factors have relevant with AD (P﹤0.05): gender, age, marital status, and cultural level, personal income, family income, family structure, the level of genetic history, whether love sports, whether the hobby is widespread, diet, Unconditional single factor Logistic Regression analysis variables are: age (OR = 0.422, 95% CI: 0.140 ~ 0.688), marital status (OR = 1.633, 95% CI: 1.304 ~ 2.036), cultural degree (OR = 0.489, 95% CI: 0.358 ~ 0.679), personal income (OR = 0.311, 95% CI: 0.140 ~ 0.688), genetic history first-degree relatives (OR = 0.347, 95% CI: 0.654) and whether love sports(OR = 3.234, 95% CI: 1.584 ~ 5.903). Conclusions: Aged people in our community, including AD,have higher rate of chronic. AD has become the main diseases and improved with age.We should pay attention to AD in the social. Female, aged, marital status, the low degree of culture, low personal and family income , alone, genetic are factors for AD; Love sports, widely hobby, reasonable diet may be protection factor to AD, in the AD of intervention and preventive measures should be paid more attention to.