Case Study On The Effect Of Fine Particulate Matter On The Hospitalization Of Respiratory Diseases In Qingdao City

Objective: 1. To investigate the influence of PM_2.5 on respiratory diseases admissions in Qingdao.2. To know the effect of short-term exposure to the particulates air pollution（SO₂, NO₂） on daily mortality rate, mortality rate of respiratory diseases and cardio-cerebrovascular diseases, outpatient rate and hospitalization rate.Methods: 1. This study was carried out in the AFFILIATED HOSPITAL OF QINGDAO UNIVERSITY in QINGDAO,China.Patients were included in the study carried out between January1 st, 2014 and December 31 st, 2015. If they were asthma, pneumonia and COPD, used a case-crossover design and logistic regression model to analyze the impact of atmospheric pollutants PM_2.5 on respiratory diseases admissions.2. Studies reached permit-in standard were collected from VIP、CNKI、Pub Med、EMBASE via online search, exposure- response data were picked up, then Stata 12.0 software was used to analyze the data; The effect size was amalgamated by fixed or random effect model.Results: 1. For the single-pollutant model, after adjusted for daily average temperature factor, the most relevant between PM_2.5 and respiratory disease admissions at lag0, A 10μg/m3 increase in PM_2.5 was associated with a 1.2%increase in hospital admissions for respiratory disease（P<0.05）.2. For multi-pollutant models, the effect of a PM_2.5 on respiratory diseases admissions remained significant after SO₂、NO₂、SO₂+NO₂ was included in the model.3. For SO₂, as the concentration increased by 10 μg/m3, the combined effect values OR/RR and confidence interval of the risk on daily mortality, respiratory diseases mortality, cardio-cerebrovascular diseases mortality in the short term was 1.009（1.006-1.011）、1.012（1.009- 1.016）、1.007（1.005- 1.008）,respectively.4. For SO₂, as the concentration increased by 10 μg/m3, the combined effect values OR/RR and confidence interval on outpatient and hospitalization rate from respiratory diseases, and outpatient and hospitalization rate from cardio-cerebrovascular diseases in the short term was 1.008（1.006- 1.01）、1.009（1.005- 1.014）, respectively.5. For NO₂, as the concentration increased by 10μg/m3,the combined effect values OR/RR and confidence interval of the risk on daily mortality, respiratory diseases mortality, cardio-cerebrovascular diseases mortality in the short term was1.014（1.011-1.016）、1.016（1.012- 1.019）、1.014（1.011- 1.015）, respectively.6. For NO₂, as the concentration increased by 10μg/m3, the combined effect values OR/RR and confidence interval of the risk on outpatient and hospitalization rate from respiratory diseases, and outpatient and hospitalization rate from cardiocerebrovascular diseases in the short term was 1.009（1.004- 1.013）、1.013（1.009-1.016）, respectively.Conclusion: 1. There was positive association between PM_2.5 and hospitalization rate from respiratory diseases in Qingdao.2. The short term increase of the concentration of SO₂ and NO₂ may lead to the increase of risks on daily mortality, respiratory diseases mortality 、 cardiocerebrovascular diseases mortality, outpatient and hospitalization rate.