The Preparation Process And Study On Quality Standard Of Qidan Granules

The agreement prescription Qidan soup of Shandong provincial hospital was applied formany years. This topic will take broth through a series of optimization of preparationtechnology, developed it into granules, aimed at improving the overall efficacy of theprescription, improve the medication compliance of patients, enlarge the appropriate crowd,and easy to carry and storage. Take formulations reform of the stilbene Qidan soup,develop stilbene Dan particles, optimizing preparation process by orthogonal designexperiment. Optimizing the best craft particles and after molding process of the research.Obtaining the thin layer chromatography of index component for Salvia miltiorrhiza,astragalus root, epimedium, Gordon euryale seed, Chinese angelica, ink dry lotus, cookedlateral root of aconite, thus identifiing the effective components. Using HPLC technology,combined with the standard comparison and literature data, obtain stilbene Dan particlesmore index components of liquid chromatogram, calculate content and establish its qualitystandard.This experiment successfully prepared Qidan Granule.The quality control method isfeasible, its quality control method is scientific and reasonable; for clinical use andproduction quality control to provide quality assurance, and also provides a reference forthe relevant reformation of formulation and establishment of quality standards of QidanGranule.