| Object:clinical study on treatment of headache from liver, establishing characteristics of liver of TCM diagnosis and treatment of headache, optimize programme of TCM diagnosis and treatment of headache.Method:reference 1988 International Headache Association standard under developed repeatedly attack sexual tension type headache diagnosis standard, reference national technology supervision Council TCM clinical clinic terms under national standards (1997) developed TCM syndrome differentiation card standard (liver-fire ascending syndrome Shang inflammatory card, and liver Yang of wind card, and liver Yu blood stasis card) into patients, used random, and double blind, and comfort agent controlled of clinical research, treatment group with pure Chinese medicine group party, to highlight TCM of advantage. Controlled group given color aroma and treatment group Chinese medicine decoction basic consistent of comfort agent; treatment group to Qing liver Xie fire pain soup, prescription by crude, and Dan skin, and radix paeoniae Rubra, and figwort, and gentian grass, and put semen cassiae, composition, or to flat liver out wind pain soup mixture, prescription by tianma, and hook rattan, and put semen cassiae, and Sichuan cattle knee, and scutellaria baicalensis, and glucosides, and crude, and fried gardenia, and chuanxiong, and chrysanthemum, and Antelope powder, composition, or to soothing liver huoxue pain soup mixture, prescription by bupleurum, Angelica, chuanxiong, crude, Radix paeoniae Rubra, glucosides,, composition; day a agent, min two times clothing, each 100ml; course for 4 week. Evaluation included headache onset, extent, duration, frequency, number of days of TCM syndrome (certificate of primary and secondary). Above the diling,er. si,BA week observation index respectively. Course of one month, after Excellent cases in a 1-month follow-up. Avoid using other pain relief drugs during test.Results:1. effects of headache. Qing liver Xie fire group neural sexual headache effect of comparison, total effective rate for 90.8%, controlled group of total effective rate for 61.9%; flat liver out wind group treatment group of total effective rate for 82.6%, controlled group of total effective rate 60%; soothing liver huoxue group treatment group of total effective rate for 85%, controlled group of total effective rate 52.6%treatment group effect better than controlled group (P<0.05). Two groups of medication of headache intensity score after 4 weeks, treatment set significantly lower than the control group (P<0.05).2. the effect of TCM syndrome. Comparison between curative effect of TCM syndromes and treatment efficiency of 69.2%, the total effective rate of 93.8%, control efficiency of 57.2%, the total effective rate of 71.4%, treatment efficacy significantly better than control groups (P<0.05). Two group comparison of integration of TCM syndromes after taking 4 weeks treatment set significantly lower than the control group (P<0.05).3. the trial, no apparent adverse reaction in patients with treatment groups, are more tolerant. Individual patients after medication sometimes soft, increasing phenomenon, but many insist on treatment, upon completion of the course no significant discomfort. Blood uric routine before and after tests, liver and kidney function (ALT, and Cr, and BUN), ECG no exception, safety testing ideal.Conclusion:the liver and purging fire, pinggan Xifeng law, soothing the liver and promoting blood circulation for treatment of headache in reducing the number of attacks of headache, headache, and improve the curative effect of TCM syndromes and other aspects of better than control groups. Surface of the test results with high safety, side effects of traditional Chinese medicine in treating the disease of small features. From exploring in depth in the field of traditional Chinese medicine treating nerve headache in effective methods and drugs, have important clinical and social value. |
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