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Zhengqingfengtongning Iontophoresis Plus Clinical Studies, Oral Administration Of The Treatment Of Osteoarthritis Of The Knee

Posted on:2012-03-01Degree:MasterType:Thesis
Country:ChinaCandidate:G M YuanFull Text:PDF
GTID:2204330335959739Subject:Integrative Medicine Internal Medicine
Abstract/Summary:PDF Full Text Request
Objective:to observe the introduction and oral ZhengQing FengTongNing ion of knee osteoarthritis clinical symptoms and signs of improvement, preliminary discussion ZhengQing FengTongNing oral and ion into two methods of taking clinical curative effect is antagonist or stack for clinical treatment osteoarthritis, provide certain basis.Methods:90 cases Knee osteoarthritis (osteoarthritis, slander KOA) patients, randomly divided into three groups, each group of 30 cases, the treatment group ZhengQing FengTongNing slow-release tablet to oral, every time 60mg twice a day, add ZhengQing FengTongNing injection (1ml/joint times,2 times per day,1ml:25mg) ion import; The control group 1 give ZhengQing FengTongNing slow-release tablet oral,every time 60mg twice a day, add ion import saline 1 ml/joint* times,2 times per day;The control group 2 oral placebo,each 60mg twice a day, add ions ZhengQing injection (FengTongNing import 1ml/joint* times,2 times per day, 1ml:25mg). Treatment for 20 days, observing a period of treatment.Results:1.Effect of TCM disease classification of TCM treatment:three groups after illness classification, the treatment group of 30 cases of 17 cases, mild, moderate, and severe 3 cases 10 cases.30 cases of control group 1 patients, mild, moderate 12 cases of 14 cases, severe 4 cases. The control group 2 patients, mild 12 cases of 30 cases, moderate in 11 cases, severely 7 cases. The treatment group and control group 1 comparison, two groups after treating illness grading comparative differences TCM was not statistically significant (P>0.05). The treatment group and control group 2 comparison, two groups after treating disease classification TCM no significant difference (P>0.05), indicating that ZhengQing FengTongNing ion import for osteoarthritis oral medicine with illness grading influence was statistically significant.2. The total score syndromes influence:three groups of patients before treatment groups syndrome integral difference was statistically significant (P>0.05). Three groups of patients after treatment in groups of TCM syndrome points compared greup statistically significant (P<0.01); The treatment group and control group syndrome were two comparison, differences between groups points are statistically significant (P<0.05), treatment group was higher than the two control group.3. The influence of clinical symptoms:three groups of patients before and after treatment ZhengQing WOMAC integral comparison, FengTongNing can significantly improve patients with knee pain, knee stiff and knee physiological function (P<0.01),the treatment group than two in control group (P<0.05).4. WOMAC curative effect of influence:three groups WOMAC) clinical curative effect evaluation(,according to the results of the treatment group total effectiveness, total effective control group 183.33% respectively group, 2 general efficient 66.67% aloin treatment group and control group, two patients with clinical curative effect (WOMAC) were compared is statistically significant difference (p<0.05).Conclusion:ZhengQing FengTongNing oral and ion import treatment knee osteoarthritis can significantly improve the clinical symptoms and joint function, for knee osteoarthritis have analgesic and anti-inflammatory action; Two ways at the same time give medicine curative effect is better than pure oral or ions into the drug.
Keywords/Search Tags:ZhengQing FengTongNing, Evergreen cane alkali, Ion import, Knee osteoarthritis, Clinical studies, WOMAC score
PDF Full Text Request
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