Hyperprolactinemia Reproductive Hormone Changes And Correlation Study Of Hepatic Depression Syndrome

The incidence of hyperprolactinemia in women with genital dysfunction is 9% -17% . It is an ordinary disease that does harm to female reproductive healthy. In this kind of people , there is a group of symptoms relate to liver-Qi stagnation , such as irritability , distending sensation in breast , distending pain in the hypochondrium and lateral lower abdomen, irregular menstruation .Objective: researching the changes of serum sex hormones and the correlation with liver-Qi stagnation in HPRL women.Method: selecting .24 females according to the accepting standard to form the HPRL-group, and selecting 21 females who are of the similar diseases in the same term to form the controlled-group . Observing their serum sex hormones including PRL LH, FSH,E2, P, T, and their clinical main symptoms , and scoring their symptoms related to liver-Qi stagnation according to the quantified standard. Then analyzing the variables through SPSS(statistical package for the social science).Results: comparing to the controlled-group , the HPRL-group has lower FSH, LH, E2 level, higher T level, and only the FSH level has significant difference. In the HPRL roup, serum PRL has reverse relation with E2, LH, FSH, T, among them E2, LH have significance. The two groups of scores and degree of liver-Qi stagnation have significant difference. In the HPRL roup, liver-Qi stagnation has positive relation with PRL and T, has reverse relation with E2, and only PRL has significance.Conclusion: HPRL can inhibit the synthesization and secretion of the serum E2, LH, FSH. So it can lead to female physiological and genital dysfunction. HPRL has a close relation with liver-Qi stagnation . So syndrome differentiation and treatment should focus on this. And psychological therapy becomes a necessary part of compositive treatment.