Liver Soup To Fat Rather Clinical Study Of Treatment Of Nonalcoholic Fatty Liver

Objective:To observe the clinical effect and blight of The Traditional Chinese herb Medicine qu zhi ning gan Tang (QZNG) to nonalcoholic patients with fatty liver, which are belong to Blood stasis and damp-turbid and depression of heat sympathy by TCM Bianzheng. To evaluate objectively the validity and security of QZNG in treating fatty liver, inquiry into its function mechanism, guide its in the clinical application. Methods:The qualified test-acceptors were divided randomly into two groups: the treatment group and the control group. There were 24 patients in each group without significance in sex, age, symptoms pattern between two groups (P>0. 05). The treatment group took The Traditional Chinese herb Medicine QZNG, one dose a day. The control group took Dong Bao Gan Tai (DBGT) 3 pains three times a day. Refer to the clinical directive rule of new Chinese herb and development of fatty liver research the time of treatment was sure to three months. According to the observed results, evaluated the treatment effectiveness. 1The observed of treatment effectiveness. (1) Accumulated the score of symptoms and signs. (2) Weight exam. (3) Blood Lipid (TC, TG) and liver function (AST, ALT, GGT) test. (4) B type ultrasonic test. 2 Security tests include blood-routine, urine-routine, stood-routine, kidney function and ECG. At last, analyze the statistic data with two sides test. When P<0. 05, it was considered as statistic meanings. Results:1 The total efficient of the treatment group is 91. 6%, of the control group is 87.5%. The total treatment effect of both groups is similar (P>0. 05). This indicating the treatment of QZNG is similar to the treatment of DBGT.2 After three months treatment, both groups can improve significantly the total integral calculus of symptoms and advertises (P<0. 001). And the treated group is significantly better than the control one (P<0.05).3 Both groups can reduce the weight (P<0.05). There is no significant difference on the two groups (P>0.05).4 Both groups can reduce significantly serum transaminase (AST, AST, GGT)and blood lipid (TC, TG)(P<0.05). There is no significant difference on improving liver function, reducing serum total cholesterol (TC) (P>0. 05). But has significant difference on reducing serum triglyceride (TG) (P<0. 05).5 On lightening the degree of pathological changes of liver reflecting by B type ultrasonic, both groups have significant difference (P<0. 05). Compared with the control group, the treated group has a better result (P<0. 05).6 In the aspects of safety observing, both groups have no bad reaction. Conclusions:By three months treatment, the clinical effect of QZNG is a litter superior to DBGT, but in improving the total integral calculus of symptoms and advertises, reducing serum triglyceride (TG), reducing weight and lighting the degree of pathological changes of liver reflecting by B type ultrasonic, QZNG is much better than DBGT. Therefore, QZNG is adapt to fatty liver patients with blood stasis and damp-turbid and depression of heat. It can either reduce blood lipid or protect the liver function and reduce serum transaminsase. It has been certified a safe and effective prescription of Chinese herbal medicine by clinic experiment. It deserves the clinical expansion.