| Radix Polygalae is the root peels of a Polygala tenuifolia family perennial herb Polygala tenuifolia Wild or ovum leaf Polygala sibirica.it is stated from 《shen nong ben cao jing 》 , and it is considered as the key medicine which raises the life, it can benefit intelligence ,calm the nerves and have function of reducing phlegm etc. and it can used in much dreams of insomnia, palpitate, etc. Consulting successive dynasties herbal monograph, there is not recordation about its poison , but forefathers find it has side effect of " throat " in the course of applying, it takes the bad reaction of intestines and stomach , often causing the nausea, vomitting etc. so often for external use. Earlier researches show that the toxicity of miyuanzhi and side effects to the intestines and stomach is smaller, its drug effects of various fields have not been influenced. On this basis, we study further to the cute toxicity, toxic experiment, intestines and stomach mucous membrane harm and impaction on intestines and stomach function ,etc of shengyuanzhi and miyuanzhi . The result shows : toxicity of miyuanzhi is lower, inhibition to intestines and stomach is smaller .and the main element of shengyuanzhi is saponin .its toxic reaction is in the gastrointestinal tract. |