Nano Rare Earth Carboxylic Acid 8 - Hydroxyquinoline Ternary Complexes Synthesis, Characterization And The Role Of K562 Leukemia Cells

Recently, researchers have been making rapid progress in the development of various antibacterial and anticancer. Owing to less posionousness and wide antimicrobial spectrum , the newly antibacterial of rare earth complexes attracts more and more people to research . Meanwhile, research about complexes neodymium with molybdate acid or tungstic acid for anticancer attract more eyes.On the basis of the two above points, eight new solid ternary complexes of rare earth with molybdate acid and 8-Hydroxyquinoline, eight new solid ternary complexes of rare earth with tungstic acid and 8-Hydroxyquinoline were synthesized. Their composition are characterized by elemental analysis , molar conductance , IR , Raman , UV-VIS . The compositions of the complexes were confirmed to be RE(MoO₄)Hq·3H₂O, RE(WO₄)Hq·3H₂O (RE=La³⁺,Ce³⁺,Pr³⁺,Nd³⁺,Sm³⁺,Eu³⁺,Er3+,Y³⁺). The stability of heat was proved by the data of TG-DTA .The antibacterial activities testing indicate that all these solid ternary complexes have antibacterial ability against Escherich coli, Staphy lococcus aureus ,Candida albican. Meanwhile, the antimicrobial spectrum more broad and durable quality, are good antibacterial.K562 cancer cell badgered by complexes were researched by MTT, Flow Cell Equipment, TEM. The results indicate that K562 cancer cells were withered by the complex and the ability was changed with the concentration of complexes, time and cell.