Dan The Gardenia Xiaoyaosan Flavored On Diabetic Patients With Depression, The Role Of Clinical Observation

[Objective]Through clinical observation,diabetes and depression in patients with symptoms of a Chinese medicine,the choice of Liver depression and spleen deficiency syndrome characteristics of diabetes and depression permit,with Danzhi Xiaoyaosan Modified psychological intervention,and hypoglycemic antidepressant medicine for the control group And then explore Chinese medicine emotional factors and the relationship between diabetes control blood glucose.[Information]Hubei Province of Chinese medicine hospital treated from 2005 to 2007 at the same time with "diabetes" and "depression," and spleen deficiency in patients with Liver Depression is certified 102 cases studied retrospectively.Selected information requirements1.Diabetes diagnostic criteria adopted Chinese Medical Association Diabetes Association in 1999 adopted by the "new diabetes diagnosis and classification" standard:the fasting plasma glucose(FPG)≥7.0mmol / L or 2 hours postprandial blood glucose(2HPG)≥11.1mmol /L."Drink more, polyuria,more food,weight loss," symptoms are not obvious to the other days of the diagnosis.2.Depression diagnosis reference to the "spirit of the Chinese Classification and Diagnostic Criteria disease"(second edition),Hamilton Depression Rating Scale(HAMD)(Schedule see below):24≥20 points,and ≤35 points to.3.Reference 1995 published "Chinese syndrome diagnosis of efficiency stan2dards," Diabetes,depression,diagnostic criteria,the Chinese Diabetes,Depression,spleen deficiency Liver Depression is certified, manifested as depression,burnout fatigue,palpitation insomnia,chestthreatening nausea,gastrointestinal discomfort,constipation,or greasy white tongue fur,pulse string or fine.4.Age range of 18-70 years old.5.Willing to accept clinical trials and to forecast better compliance.6.Within one week before treatment without the use of other antidepressants,and within two weeks without the use of Monoamine oxidizes enzyme preparation,and nearly two weeks in the basic stability of blood glucose,HBA_1c≥6.9%and≤11.5%.[Method]At the same time the choice of "diabetes" and "depression," and is certified Liver depression and spleen deficiency,102 cases were randomly divided into groups of Chinese medicine,Western medicine group,blank group, all subjects of the original foundation and diabetic hypoglycemic drug therapy remain unchanged.Chinese medicine groups:using Modified Dan zhi Xiaoyaosan decoction 150ml bid;WMgroup:Deanxit one qd;blank control group: only by hypoglycemic drugs for 12 weeks,observing indicators:HAMD such as scale,the Chinese symptoms,glucose,HBA_1c.[Results]1.HAMD three groups before and after treatment,compared HAMA Scale Integration:After treatment,the two are blank group increased slightly, and treatment there was no significant difference compared to the former P＞0.05,two groups of western medicine after treatment than before there was a significant reduce P＜0.01;and blank group after treatment there was a significant difference between P＜0.01;WM group is superior to the Chinese Medicines Board.HAMD two points after treatment than P＜0.01,P HAMA points than＜0.052.FBG three groups before and after treatment,2hPG,HBA^1ccomparison, the three groups after treatment gaps are rising,FPG P＜0.01,2hPG P＜0.05, there was significant difference between the three groups after treatment of Chinese medicine are very significant drop P＜0.01.WM group have,in varying degrees,also fell,but only FPG,2hPG P＜0.05,after the three treatment groups compared with the blank,medicine group were significantly decline.FPG,2hPG P＜0.01,HBA^1cP＜0.05,two groups of different levels of coconut oil decreased,but only FPG,2hPG P＜0.05.WM group was not significantly different between.3.Group Syndrome major effects:a maximum rate of the patients from the five symptoms by effective,ineffective inspection,the results of anxiety, depression,insomnia maximum performance from the treatment results,in the western medicine treatment of the two groups after the of the major syndromes are varying degrees see improved very significantly better than control groups,including anxiety and depression improvement,Chinese medicine group than in the high proportion of the WM group,P＞0.05,the difference was not significant,and the insomnia,fatigue weakness,bulging nausea improvements Chinese medicine is better than medicine group P＜0.05.[Conclusion]Modified Danzhi Xiaoyao san be significantly improved in patients with depression,somatic symptoms,such as insomnia,mood improved after an increase of the compliance of patients and reduce the negative sentiment caused by insulin resistance,thus beneficial to the control of blood sugar, may be associated with depression,diabetes an effective method of treatment.