| Objective:C is a medicine which is considered as emergency treatment medicine used in traditional Chinese medical hospital.It can relieve fever, antibiosis,antivirus,anti-inflammatory,an so on.But it has adverse effects such as anaphylaxis,hepatic injury,thrombocytopenia and so on.we compatibility C with H for Attenuation and synergia.methods:use rat long term toxicity experiment for Attenuation;use in vivo antivirus experiment,jimpy mice ear swelling experiment,jimpy mice cotton ball granuloma experiment,capillary permeability experiment and rabbit relieve fever experiment for synergia.results:CH injecta can raise the PLT than C,and it's toxicity for liver and kidney is weak than C;CH injecta can rasie ADV—3 mouse and H1N1 infectionmouse death protection rate,degrade mortality,inhibit pneum-exponent and against body weight descent;CH injecta can inhibit ear swelling caused by xylene,jimpy mice cotton ball granuloma and capillary permeability,the inhibition ratio is higher than C;CH injecta can degrade rabbit's body temperature than C.conclusion:①CH injecta's attenuation is better than C;②CH injecta's antivirus is better C.③CH injecta's antiinflammatory effect is better than C.④CH injecta's relieve fever is power than C. |
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