Kam Lanterns Fruit's Chemical Composition And Purification Technology

Jindenglong, named also Hongguniang or Guajindeng in Chinese, is a kind of plant of Physalis alkekengi L. var. franchetii (Mast.) Makino. Its fruits are a common Chinese traditional medicine, used for detumescence, relieving a cough, dissipating phlegm, diuresising, strengthening heart, expelling toxin, clearing heat and removing clampness. It is stated in proved recipe that the fruits of Physalis alkekengi L. var.franchetii (Mast.)Makino are capable of treating diabetes mellitus, which is also proved by pharmacology.In this thesis, ten compounds are isolated from the extract of the fruits of Physalis alkekengi L. var.franchetii (Mast.)Makino by solvent extraction, silica gel column, Sephadex LH-20 column and recrystalizition. According to the physical and chemical characteristic and spectral method, their structures are identified as (1)β-sitosterol; (3) dancosterol;(4) 4,7-didehydro-neophysalin B; (5) physalin P; (6) 5-Methyl-3-pyridinecarboxylic acid;(7) physalin D;(8)5-hydroxymethyl-furoic acid;(9)1.5 dimethylcitrateFor the first time, it establish method for determining the content of the fruits of physalis alkekengi L. var. franchetii(mast.)mskino. Determate the content of 4,7-didehydro-neophysalinBand physalin P by HPLC.The results are0.0176%and0.059%, respectively. For the first time,the optimum extraction and purification conditions of the fruits of physalis alkekengi L. var. franchetii(mast.)mskino. Were determined by the orthogonal test and the content of physalin P as index was detected by HPLCso as to enhance the content of physalin P .