Synthesis Of 3,5-diamino-multi-nitropyridine And Its Derivatives

Recently, the multi-nitryl-amino-pyridine compounds and its derivatives, most of which had characteristics of high-energy, high formation enthalpy, low sensitivity, thermal stability, good detonation and heat resistance, have been widely studied as a new high-energy, low-insensitivity explosive sorption to TATB. Some of them have been used in some special areas of high temperature as well as insensitive munitions, propellant powder, propellants and civilian explosives.In this paper, by directly nitrating Aminopyridine and protected aminopyridine, which were prepared from 3,5-dimethylpyridine in simple reactions of three steps including oxidation of methyl, amination and Hofmann degradation, the feasibity of multi-nitryl-amino-pyridine was investigated:1. The influence factors of every step were studied, so 3,5-diaminopyridine and 3, 5-dimethoxycarbonylaminopyridine can be synthesized efficiently.2. There was no nitrification products by directly nitrating 3,5-diaminopyridine, although some nitration systems (HNO3/H2SO4, H2SO4/KNO3, AC2O/HNO3 and so on)have been applied.3. The results of nitrating 3,5-diacetaminopyridine,3,5-diethoxycarbonylaminopydine,3, 5-dimethoxycarbonylaminopydine and its nitrogen oxide were studied. Especially, nitrification of 3,5-dimethoxycarbonylamino pyridine and its nitrogen oxide were more easier than 3,5-diacetaminopyridine and 3,5-diethoxycarbonylaminopydine. Nitrification products including 3,5-dimethoxycarbonylamino-2-nitropyridine,3, 5-dimethoxycarbonylamino-2-nitropyridine nitrogen oxide,3,5-dimethoxycarbonylanm-ino-2,6-dinitropyridine and 3,5-dimethoxycarbonylamino 2,4,6-trinitropyridine were synthesized.3,5-diamino-2,6-dinitropydine is synthesized by hydrated 3, 5-dimethoxycarbonylamino-2,6-dinitropydine.All products were characterized by modern analytical methods including IR, MS,1H NMR and elemental analysis, and their structures are assured.