Analysis Of Utilization Of Antihypertensive Drugs In Three Class-vary And Grade-A Hospitals In Tianjin

Objective:Through investigating the application of antihypertensive drugs in three Class-vary and Grade-A Hospitals in Tianjin, comparing Hypertension Guideline, analyzing the use of antihypertensive drugs in order to provide the scientific basis for the rational use and management of antihypertensive drugs.Methods:The retrospective investigation in respect of the tendency of using antihypertensive drugs in three Class-vary and Grade-A Hospitals in Tianjin were statistically analyzed from July to December in 2009.The three hospitals include the Class-3 Hospital, Class-2 Hospital and a Community Health Center in Hexi district of Tianjin. The drug utilization including the dates, the patient sex, age, drug name,consumption sum, and the combination drug use of antihypertensive drugs. The money for consume, the defined daily doses (DDDs) and defined daily dose cost (DDDc) were investigated with Microsoft Excel 2003. The utilization characteristics and development trend of antihypertensive drugs were discussed.Results:Of the outpatient prescriptions reviewed, three hospitals involved use of antihypertensive drugs, of whom, male represented more than female and antihypertensive drugs were mostly used in patients aged between 50 to 80 years. The classes of antihypertensive drugs in the Class-3 ranked by the defined daily doses (DDDs) were Calcium channel blockers (CCB),angiogenesisⅡreceptor antagonist (ARB),angiogenesis converting enzyme inhibitors(ACEI),β-receptor blockers (B-RB) and compound preparation; Class-2 Hospital:CCB,ACEI,traditional Chinese medicine,ARB,andβ-RB; Community Health Center Hospital:CCB,traditional Chinese medicine,ARB,ACEI and B-RB. The classes of antihypertensive drugs in the Class-3 ranked by the money for consume were CCB,ARB,β-RB,ACEI and compound preparation; Class-2 Hospital:CCB,ACEI,traditional Chinese medicine,ARB andβ-RB; Community Health Center Hospital:CCB,ARB,traditional Chinese medicine,ACEI andβ-RB. Drug utiliztion index (DUI) about is one.Of the inpatient prescriptions reviewed, three hospitals involved use of antihypertensive drugs, of whom, female represented more than male and antihypertensive drugs were mostly used in patients aged between 60 to 90 years. The classes of antihypertensive drugs in the Class-3 ranked by DDDs were CCB,diuretics,ACEI,ARB and traditional Chinese medicine; Class-2 Hospital:CCB,diuretics,ACEI,ARB andβ-RB. The classes of antihypertensive drugs in the Class-3 ranked by the money for consume were diuretics,CCB,α-RB,ACEI and ARB; Class-2 Hospital:CCB,diuretics,ACEI,ARB and traditional Chinese medicine. Drug utiliztion index (DUI) about is one.Conclusions:The utilization of antihypertensive drugs were basically reasonable in three Class-vary and Grade-A Hospitals in Tianjin. Keeping good control of blood pressure meanwhile protecting target organs. CCB,ACEI,ARB,β-RB and diuretics dominate in the antihypertensive market in Tianjin. The top more ten of DDDs was in accordance with antihypertensive drugs indicates. Prolonged action preparation,compound preparation and the combination drug use of antihypertensive drugs are helpful for treating hypertensive disease. The doctors of the three hospitals followed scientific, safe and effective, applicable and economical principles in respect of the selection of antihypertensive medications. In line with the domestic and abroad general medication situation, the antihypertensive drugs are characterized by complicated categorization, wide variety, and widespread clinical application. It's necessary to train the physicians to strengthen their sense of responsibilities and reasonable prescriptions, to reduce irrational administration, and to make the service truly patient-oriented. For some time to come, antihypertensive drugs of long-lasting efficiency, less adverse reactions and low cost would be welcome in our hospital, in line with the development trend of antihypertensive drugs.