Study Of Optimized Program On Integrative Medicine In Treatment Of Chronic Ulcerative Colitis

Objective: The study is based on chronic ulcerative colitis (UC) to the patient, and the incidence of disease characteristics and evolution of pathogenesis, take TCM & western medcine, identifying diseases and dialectical, internal governance and external governance and the combination of global and local methods, to promote the effective and easy treatment. Methods: A total of 140 cases of election observation of objects, of which 60 patients with active stage, 80 patients in remission. Activities were divided into two groups of experimental group (30 cases), to SASP 1g / 4 times / day, oral, combination of oral and retention -enema of TCM. The control group (30 cases), to SASP 1g / 4 times / day,oral,and retention -enema of western medicine; remission are randomly divided into two groups, experimental group (40 cases), oral treatment with traditional Chinese medicine, the control group (40 cases), given SASP 1g / time, 2 times / day, oral maintenance therapy. A course of 8 weeks, respectively, clinical efficacy, clinical symptoms, symptom points, the performance of colonoscopy mucosa, as well as ESR, CRP, serum IL-1,IL-6, IL-10 and other indicators, medication side effects compare the incidence of Follow-up six months to observe recurrence rate.Result:1. activities integrated in the clinical efficacy in patients, symptom scores TCM, TCM syndromes, colonoscopy mucosa, the two groups have different levels to improve the role, but the experimental group than the control group (P <0.05 or P <0.01) ; in histopathology, serum ESR, CRP, IL-1,IL-6, IL-10 values are also significant improvements in terms of the role, but there was no significant difference (P> 0.05). 2. Comprehensive efficacy in clinical remission, TCM symptom scores, the efficacy of TCM to improve the effect of two different degrees, but the experimental group than the control group (P <0.05 or P <0.01), mucous membranes in the efficacy of colonoscopy, Clinical pathology, serum ESR, CRP, IL-1,IL-6, IL-10 also significantly improved the value of aspects of the role, but there was no significant difference (P> 0.05); in drug side effects and recurrence rate, regardless of active And mitigation of the test group was significantly lower than the control group (P <0.05).Conclusion:According to chronic ulcerative colitis to the patient, stage of disease pathogenesis and disease characteristics and evolution, by integrative medicine, TCM orally and retention-enema,together with western medicine orally in activies, oral administration of Chinese medicines in remission duration, the implementation of "syndrome differentiation" of the individual treatmentprinciples, clinical comparative observation, reliable effect, can significantly reduce drug side effects and recurrence rate for Integrative Medicine UC optimization was proposed to provide effective methods and ideas.