The Clinical Observation On Clearing Heat And Resolving Dampness Principle In The Treatment Of Eczema And Its Influence On Serum ECP Level

Purpose:Eczema is inflammatory and allergic reactions of skin due to varieties of internal and external factors, and generally considered more closely related to type IVand I allergic reaction. In Modern medicine, both eczema and contact dermatitis are allergic inflammatory skin disease. Professor Chen-Li summarizes that spleen deficiency and damp accumulation leading to internal dampness stagnation is fundamental pathogenesis of eczema, based on the analysis of traditional Chinese medicine theory, personal clinical experience and new research findings of western medicine.In our study,the principle of invigorating spleen and dispelling dampness principle and herbs decoction named'CHU SHI YIN'were determined according to the etiology and pathogenesis of subacute and chronic eczema, which aimed to observe the efficacy of the formula in the treatment of subacute and chronic eczema, meanwhile its mechanism was discussed.In addition to understanding of the close relationship between eczema and type IV allergic reaction, recognition that type I allergic reaction and serum eosinophil change are also associated with pathogenesis of eczema. So in our study, the level of the eosinophil cationic protein in serum were tested before and after the clinical observation course in order to obtain some new findings between between pathogenesis of eczema and type IVallergic reaction and its indicators of serum ECP. Meanwhile, the influence of herbs decoction on the clinical process of eczema patients and on their serum ECP changes were observed in order to realize the clinical significance of serum ECP in eczema. Method:Select compliant 60 cases of eczema patients were divided into treatment and control groups to the spleen for the treatment of the principles of dehumidification, dehumidification prescription medicine used to drink. Based medicine cetirizine as control, were treated for 4 weeks. Reference to October 1990 established Chinese Medicine Press ("common disease diagnosis and therapeutic evaluation standards "and in June 1998 the People's Medical Publishing House to develop a "cure disease diagnosis based on improved standards" for patients. At the same time, Two groups were detected before and after treatment eosinophil cationic protein (ECP) level changes. using EASI score, observation area before and after treatment and severity of skin lesions and to investigate changes in patient satisfaction with treatment.Result:Treatment group symptom and signs rate of 93.33%, slightly higher than the cetirizine group, but not statistically significant. Eosinophil cationic protein (ECP) levels of detection:the treatment group decreased levels of ECP levels than the control group, indicating that the control group compared to Western medicine, Chinese medicine treatment group ECP levels in patients with eczema and better regulation.Meaning:To investigate the treatment of eczema spleen desiccant effect and impact on serum ECP, the incidence of eczema can be better to find the relationship between serum ECP and thus further optimize the clinical treatment of eczema.