| Objective:This topic was to observe the injectable lamps spend grain to merge unstable angina patients with hyperlipidemia, and to find the clinical curative effect for future clinical treatment of coronary heart disease combined with western routine provide method and maybe certain reference by recording the whole blood viscosity, blood fat and anginal attacks, ECG changes before and after the treatment, and monitor stool, urine, blood routine examination, liver and kidney function changes of the between two groups.Materials and methods:Sixty-two cases of merge unstable angina patients with hyperlipidemia from Puai hospital in wuhan city from May 2009 to May 2010 were selected. All cases followed 2003 cardiovascular magazine editors committee "cardiovascular disease" guidelines and suggestions of unstable angina and hyperlipidemia diagnosis criteria.62 cases were randomly divided into the treatment group 30 cases and control group 32 cases. The treatment group consists of male 16 cases, female 14 cases, age range from 45-72, with an average age of 60±5.77 years old,14 cases with amalgamating hypertension,10 cases with diabetes,3 cases with chronic myocardial infarction,3 cases with abnormal glucose tolerance; The control group male 17cases, female 15 cases, age 44-70 years old; with average age 58±7.50 years old,16 cases with amalgamating hypertension,9cases with diabetes,5 cases with chronic myocardial 3 cases with abnormal glucose tolerance, no significant.difference was found in gender, age, duration, and complications between 2 groups (P> 0.05), patients of 2 groups were given western medicine therapy to unstable angina and other treatments such as buck, hypoglycemic, etc. The treatment group give lamps spend grain injection 50mg join 0.9% sodium chloride 250ml intravenous drip per day by two weeks. The control group was simply received routine medicine. During treatment for lifestyle interventions, such as giving up smoking and avoiding eating too much, wine, emotional overwork. Whole blood viscosity, blood fat, anginal attacks and the amount of nitroglycerin usage, electrocardiogram ST-T change were observed before and after the treatment. Stool, urine, blood routine examination, liver and kidney function, before and after treatment were observed as safety index.Results:Whole blood viscosity, blood fat, anginal attacks, and ECG changes before and after the treatment were monitored in the 62 cases with unstable angina and hyperlipemia group. In treatment,12 total effective cases (40%), 14 effective cases (46.7%),4 invalid cases (13.33%),0 aggravated cases, the total effective rate was 86.67%; In control,9 total effective cases, (28.13%), 15 effective cases (46.88%),8 invalid cases (25%),0 aggravated cases, the total effective rate was 75%, there were significant difference between the two goups (P< 0.05). As ECG changes, was concerned in treatment group,16 total effective (53.33%),9 effective cases (30%),5 invalid cases (16.67%),0 aggravated cases, the total effective rate was 83.33%; In control group,8 total effective cases (25%),13 effective (40.63%),11 invalid cases (34.38%), the total effective rate was 65.63%, there was of statistically differences(P< 0.05). Blood viscosity and lipid changes anginal attacks were significantly different between the two groups in treatment group(P< 0.05). There were of no significant differences in urine and stool routine analysis, liver and kidney function changes before and after the treatment (P> 0.05). Conclusion:In 21th century, coronary heart disease has become one of the most common causes of human death, not only in the developed countries, but also in the developing countries. It has become a major public health problem. The injectable lamps spend grain can reduce patients whole blood viscosity, blood fat and expanding coronary artery, improve microcirculation thus decrease anginal attacks, and it is safe and of no obvious adverse drug reaction. |
PDF Full Text Request