Establishment Of The Upper Urinary Tract Calcium Oxalate Lithiasis Diagnostic Methods

To make qualitative analysis on urinary calculi by infrared spectroscopy andinvestigate the percentage change of urinary calculi. To analyze calcium oxalate stone patients, various blood and urine biochemical Parameters. Found the cause of metabolic disturbance which make stone formation. Established the etiological foundation for the clinical treatment and prevention of calcium oxalate stone. MethodsThe datas of257patients in hospital were colleeted between June2011and April2012. To analysis the urinary stones by infrared spectroscopy.76cases of renal stones patients and50case of normal volunteers with non-associated urinary stones were analyzed the blood and24h urinary biochemical parameters. Blood biochemical parameters included Serum sodium,blood calcium,blood chloride,creatinine, parathyroid hormone (PTH).24h urinary biochemical parameters included urine volume, uric acid, calcium, urine magnesium, urine phosphorus, urine oxalic acid, urine folic acid. To use Independent T test sample and the ehi square test to analysis. Results1. The rate of pure calcium oxalate stone, mixed calcium oxalate and carbonatephosphatic stone, pue cystine stone, calcite, pure urate stone, mixed uric acid and calcium oxalate stone, mixed ammonium uric acid and calcium oxalate stone, pue carbonate phosphatic stone, mixed carbonate phosphatic stone and calcium oxalate stone, pue six water magnesium ammonium phosphate stone, mixed six water magnesium ammonium phosphate and carbonate phosphatic stone and calcium oxalate stone was76(29.57%),99(38.52%),7(2.27%),2(0.77%),17(6.61%),13(5.06%),6(2.33%),4(1.56%),27(10.51%),2(0.77%) in257stone patients.2. The rate of calcium oxalate stone in male more than in female..There was marked different between them by ehi square test(X2=3.90, p<0.05).3. Among the76cases of the calcium oxalate stones. Hypocitraturia occurred in54case (71.05%), hyperoxaluria in20case (26.32%), hypercalciuria in11case (14.47%), high urine phosphorus15case (19.74%), low urine magnesium26case (34.21%), hyperuricosuria in15case (19.74%), low volume in55case (72.37%).4. Among the76cases of the calcium oxalate stones.The patients had two metabolic disturbances were45cases (59.21%),three metabolic disturbances were13cases (17.11%), four metabolic disturbances were2cases (2.63%), five metabolic disturbances were1cases (1.32%)5.Comparing to non urinary calculus peoples,The24h urine analysis results of urine oxalic acid, urine folic acid.,urine magnesium, uric acid, urine volume had different between them (P<0.05).6.Blood biochemistry results:Serum sodium and blood calcium were higher than non urinary calculus peoples, The blood chlorine and cretinine of the two groups had no significant different.(P>0.05).Conclusions1.The rate of mixed calcium oxalate and carbonate phosphatic stone is the highest of the257cases of urinary stones patients, The rate of pure calcium oxalate stone is the second high.2. Among the76cases of the calcium oxalate stones, there are a variety of metabolic abnormalities. The most common cuse of metabolic abnormalities is Hypocitraturia (71.05%) and low volume (72.37%). Other common metabolic abnormalities cause is low urine magnesium (34.21%), hyperoxaluria (26.32%), high urine phosphorus(19.74%),hyperuricosuria(19.74%),hypercalciuria(14.47%).3. Infrared spectroscopic analysis of Urinary Tract Stones combined with metabolic assessment can clear the etiology of upper urinary calcium oxalate stone, guiding stones prevention...